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ChemicalBook > Product Catalogue >API >Antiparasitic drugs >Antimalarial drugs >8-Hydroxyquinoline

8-Hydroxyquinoline

8-Hydroxyquinoline Structure
  • ₹837 - ₹166589.99
  • Product name: 8-Hydroxyquinoline
  • CAS: 148-24-3
  • MF: C9H7NO
  • MW: 145.16
  • EINECS:205-711-1
  • MDL Number:MFCD00006807
  • Synonyms:NCL-C55298;o-Oxychinolin;Oxin;Oxoquinoline;Oxybenzopyridine;Oxychinolin;Oxychinoline;Phenopyridine
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  • Sigma-Aldrich
  • ALFA India
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • SRL
  • ottokemi

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  • 500gm
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  • ManufacturerSigma-Aldrich
  • Product number36524
  • Product description8-Quinolinol PESTANAL?, analytical standard
  • Packaging250MG
  • Price₹5683.13
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number32502
  • Product description8-Quinolinol puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99% (perchloric acid titration)
  • Packaging100G
  • Price₹7447.6
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich
  • Product number252565
  • Product description8-Hydroxyquinoline ACS reagent, 99%
  • Packaging250G
  • Price₹14548.8
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich
  • Product number1.07098
  • Product description8-Hydroxyquinoline GR for analysis Reag. Ph Eur
  • Packaging250G
  • Price₹19840
  • Updated2022-06-14
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  • ManufacturerALFA India
  • Product numberALF-041272-18
  • Product description8-Hydroxyquinoline, ACS
  • Packaging50g
  • Price₹2854
  • Updated2022-05-26
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  • ManufacturerALFA India
  • Product numberALF-A14720-22
  • Product description8-Hydroxyquinoline, 99%
  • Packaging100g
  • Price₹3669
  • Updated2022-05-26
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  • ManufacturerALFA India
  • Product numberALF-A14720-36
  • Product description8-Hydroxyquinoline, 99%
  • Packaging500g
  • Price₹8391
  • Updated2022-05-26
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  • ManufacturerALFA India
  • Product numberALF-041272-30
  • Product description8-Hydroxyquinoline, ACS
  • Packaging250g
  • Price₹10693
  • Updated2022-05-26
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  • ManufacturerALFA India
  • Product numberALF-A14720-0E
  • Product description8-Hydroxyquinoline, 99%
  • Packaging2500g
  • Price₹30339
  • Updated2022-05-26
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  • ManufacturerALFA India
  • Product numberALF-041272-A1
  • Product description8-Hydroxyquinoline, ACS
  • Packaging1kg
  • Price₹41781
  • Updated2022-05-26
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  • ManufacturerTCI Chemicals (India)
  • Product numberH0305
  • Product description8-Quinolinol min. 99.0 %
  • Packaging25G
  • Price₹2300
  • Updated2022-05-26
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  • ManufacturerTCI Chemicals (India)
  • Product numberH0305
  • Product description8-Quinolinol min. 99.0 %
  • Packaging500G
  • Price₹9000
  • Updated2022-05-26
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  • ManufacturerSigma-Aldrich(India)
  • Product number8.20261
  • Product description8-Hydroxyquinoline for synthesis
  • Packaging250G
  • Price₹4360
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberH6878
  • Product description8-Hydroxyquinoline crystalline
  • Packaging25G
  • Price₹5574.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number36524
  • Product description8-Quinolinol PESTANAL?, analytical standard
  • Packaging250MG
  • Price₹5683.13
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number32502
  • Product description8-Quinolinol puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99% (perchloric acid titration)
  • Packaging100G
  • Price₹7447.6
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 36524 8-Quinolinol PESTANAL?, analytical standard 250MG ₹5683.13 2022-06-14 Buy
Sigma-Aldrich 32502 8-Quinolinol puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99% (perchloric acid titration) 100G ₹7447.6 2022-06-14 Buy
Sigma-Aldrich 252565 8-Hydroxyquinoline ACS reagent, 99% 250G ₹14548.8 2022-06-14 Buy
Sigma-Aldrich 1.07098 8-Hydroxyquinoline GR for analysis Reag. Ph Eur 250G ₹19840 2022-06-14 Buy
ALFA India ALF-041272-18 8-Hydroxyquinoline, ACS 50g ₹2854 2022-05-26 Buy
ALFA India ALF-A14720-22 8-Hydroxyquinoline, 99% 100g ₹3669 2022-05-26 Buy
ALFA India ALF-A14720-36 8-Hydroxyquinoline, 99% 500g ₹8391 2022-05-26 Buy
ALFA India ALF-041272-30 8-Hydroxyquinoline, ACS 250g ₹10693 2022-05-26 Buy
ALFA India ALF-A14720-0E 8-Hydroxyquinoline, 99% 2500g ₹30339 2022-05-26 Buy
ALFA India ALF-041272-A1 8-Hydroxyquinoline, ACS 1kg ₹41781 2022-05-26 Buy
TCI Chemicals (India) H0305 8-Quinolinol min. 99.0 % 25G ₹2300 2022-05-26 Buy
TCI Chemicals (India) H0305 8-Quinolinol min. 99.0 % 500G ₹9000 2022-05-26 Buy
Sigma-Aldrich(India) 8.20261 8-Hydroxyquinoline for synthesis 250G ₹4360 2022-06-14 Buy
Sigma-Aldrich(India) H6878 8-Hydroxyquinoline crystalline 25G ₹5574.88 2022-06-14 Buy
Sigma-Aldrich(India) 36524 8-Quinolinol PESTANAL?, analytical standard 250MG ₹5683.13 2022-06-14 Buy
Sigma-Aldrich(India) 32502 8-Quinolinol puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99% (perchloric acid titration) 100G ₹7447.6 2022-06-14 Buy

Properties

Melting point :70-73 °C(lit.)
Boiling point :267 °C752 mm Hg(lit.)
Density :1.0340
vapor pressure :0.221Pa at 25℃
refractive index :1.4500 (estimate)
Flash point :267°C
storage temp. :Store below +30°C.
solubility :0.56g/l
form :Liquid
pka :5.017(at 20℃)
color :White to pale yellow or light beige
Water Solubility :INSOLUBLE
Sensitive :Light Sensitive
Merck :14,4843
BRN :114512
InChIKey :MCJGNVYPOGVAJF-UHFFFAOYSA-N
LogP :1.85 at 25℃
CAS DataBase Reference :148-24-3(CAS DataBase Reference)
IARC :3 (Vol. 13, Sup 7) 1987
NIST Chemistry Reference :8-Quinolinol(148-24-3)
EPA Substance Registry System :8-Quinolinol (148-24-3)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

8-Hydroxyquinoline (8HQ) is an intermediate of halogenated quinoline anti-amebic drugs, including quiniodoform, clioquinoline, diiodoquinoline and the like. These drugs exert anti-amebic effects by inhibiting intestinal commensal bacteria, and are effective against amoebic dysentery, but have no effect on extra-intestinal amoebic parasites.8HQ is a small planar molecule with a lipophilic effect and a metal chelating ability. As a result, 8HQ and its derivatives hold medicinal properties such as antineurodegenerative, anticancer, antioxidant, antimicrobial, anti-inflammatory, and antidiabetic activities.

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