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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Other antineoplastic Drugs >Combretastatin A4 phosphate disodium salt

Combretastatin A4 phosphate disodium salt

Combretastatin A4 phosphate disodium salt Structure
  • ₹8000 - ₹30100
  • Product name: Combretastatin A4 phosphate disodium salt
  • CAS: 168555-66-6
  • MF: C18H19O8P.2Na
  • MW: 440.29
  • EINECS:1312995-182-4
  • MDL Number:MFCD00943911
  • Synonyms:Fosbretabulin disodiuM (CA4P);CoMbretastatin A4 Phosphate(CA4P);Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1-(dihydrogen phosphate), sodium salt (1:2);2-Methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl disodium phosphate;Combretastatin A4 phosphate disodium;SODIUM (Z)-2-METHOXY-5-(3,4,5-TRIMETHOXYSTYRYL)PHENYL PHOSPHATE;Combretastatin A-4 phosphate;CA-4P, Combretastatin A-4 phosphate
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Brand

  • TCI Chemicals (India)

Package

  • 20MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberC3009
  • Product descriptionCombretastatin A4 Phosphate Disodium Salt
  • Packaging20MG
  • Price₹8000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC3009
  • Product descriptionCombretastatin A4 Phosphate Disodium Salt
  • Packaging100MG
  • Price₹30100
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C3009 Combretastatin A4 Phosphate Disodium Salt 20MG ₹8000 2022-05-26 Buy
TCI Chemicals (India) C3009 Combretastatin A4 Phosphate Disodium Salt 100MG ₹30100 2022-05-26 Buy

Properties

Melting point :238-242 ºC
storage temp. :-20°C
solubility :H2O: soluble5mg/mL, clear
form :powder
color :white to beige
InChIKey :VXNQMUVMEIGUJW-XNOMRPDFSA-L
CAS DataBase Reference :168555-66-6

Safety Information

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Description

Combretastatin A4 Phosphate Disodium Salt is the salt form of Combretastatin A4, a phosphorylated microtubule depolymerizing molecule which induces tumor necrosis by regression of unstable nascent tumor neo-vessels. Studies suggest that Combretastatin A4 Phosphate Disodium Salt selectively inhibits endothelial tumor cells via disrupting VE-cadherin (vascular endothelial-cadherin). In addition, Combretastatin A4 Phosphate Disodium Salt can increase the permeability of endothelial cells while inhibiting their migration and suppress capillary tube formation via disruption of VE-cadherin. Furthermore, Combretastatin A4 Phosphate Disodium Salt can change the morphology of endothelial cells by altering their tubulin cytoskeleton.

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