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ChemicalBook > Product Catalogue >API >Fluid, Electrolyte, and Acid-Base Balance >Electrolyte Balance Pharmacology >Pamidronate disodium salt

Pamidronate disodium salt

Pamidronate disodium salt Structure
  • ₹8800 - ₹58065.3
  • Product name: Pamidronate disodium salt
  • CAS: 57248-88-1
  • MF: C3H12NNaO7P2
  • MW: 259.07
  • EINECS:260-647-1
  • MDL Number:MFCD01938386
  • Synonyms:3-Amino-1-hydroxy-1-phosphonopropyl phosphonic acid disodium salt;Pamidronate Disodium, GCP-23339A, Aminomux, Aredia;Pamidronic Acid, Sodium Salt, Hydrate;Phosphonic acid, (3-amino-1-hydroxypropylidene)bis-, disodium salt;(3-amino-1-hydroxypropylidene)bis-phosphonic acid disodium salt;disodium dihydrogen (3-amino-1-hydroxypropylidene)bisphosphonate ;PAMIDRONATE DISODIUM SALT HYDRATE;(3-AMINO-1-HYDROXYPROPYLIDINE)BIS-PHOSPHONIC ACID
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 100MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberD3921
  • Product descriptionDisodium Pamidronate
  • Packaging100MG
  • Price₹8800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD3921
  • Product descriptionDisodium Pamidronate
  • Packaging1G
  • Price₹18400
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP2371
  • Product descriptionPamidronate disodium salt hydrate ≥95% (NMR), solid
  • Packaging10MG
  • Price₹13574.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP2371
  • Product descriptionPamidronate disodium salt hydrate ≥95% (NMR), solid
  • Packaging100MG
  • Price₹58065.3
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D3921 Disodium Pamidronate 100MG ₹8800 2022-05-26 Buy
TCI Chemicals (India) D3921 Disodium Pamidronate 1G ₹18400 2022-05-26 Buy
Sigma-Aldrich(India) P2371 Pamidronate disodium salt hydrate ≥95% (NMR), solid 10MG ₹13574.55 2022-06-14 Buy
Sigma-Aldrich(India) P2371 Pamidronate disodium salt hydrate ≥95% (NMR), solid 100MG ₹58065.3 2022-06-14 Buy

Properties

Melting point :300 °C
storage temp. :2-8°C
solubility :H2O: 28 mg/mL
form :solid
color :white
Merck :14,7003
Stability :Hygroscopic
CAS DataBase Reference :57248-88-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Pamidronate disodium salt is a bisphosphonate compound, which inhibits farnesyl diphosphate synthase and bone resorption. Studies suggest that Pamidronate disodium salt stimulates polymorphonuclear leukocyte and platelet derived nitric oxide production. It is believed that this nitric oxide production can lead to a negative feedback mechanism, which could restrict the inflammatory process and reduce bone resorption. Furthermore, bisphosphonates induce endothelial cell death, cancer cell apoptosis, and nuclear factor-κB pathway activation, via the endothelial protein C receptor.

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Suppliers and manufacturers

Jigs Chemical ltd JPN Pharma Pvt Ltd Sun Pharmaceutical Industries Ltd Rivashaa Agrotech Biopharma Pvt. Ltd. Ralington Pharma Manus Aktteva Biopharma LLP Sai Prathyu Marketing Indexim International Sun Pharmaceutical Industries Ltd. Ralington Pharma.