Clodronate disodium
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- ₹25168.13
- Product name: Clodronate disodium
- CAS: 22560-50-5
- MF: CH5Cl2NaO6P2
- MW: 268.88
- EINECS:245-078-9
- MDL Number:MFCD01632786
- Synonyms:CL2MDP;Phosphonic acid, P,P'-(dichloromethylene)bis-, sodium salt (1:2);Clodronate disodium, >=98%;DICHLOROMETHYLENEDIPHOPHONIC ACID DISODIUM SALT;DICHLOROMETHYLENEDIPHOSPHONIC ACID DISODIUM SALT;DMDP;CLODRONIC ACID DISODIUM SALT;CLODRONATE DISODIUM
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 1G
- ManufacturerSigma-Aldrich(India)
- Product numberD4434
- Product descriptionDichloromethylenediphosphonic acid disodium salt
- Packaging1G
- Price₹25168.13
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | D4434 | Dichloromethylenediphosphonic acid disodium salt | 1G | ₹25168.13 | 2022-06-14 | Buy |
Properties
Melting point :>330°C
storage temp. :room temp
solubility :Freely soluble in water, practically insoluble in ethanol (96 per cent), slightly soluble in methanol.
form :Solid
color :White to Off-White
InChIKey :HJKBJIYDJLVSAO-UHFFFAOYSA-L
CAS DataBase Reference :22560-50-5(CAS DataBase Reference)
storage temp. :room temp
solubility :Freely soluble in water, practically insoluble in ethanol (96 per cent), slightly soluble in methanol.
form :Solid
color :White to Off-White
InChIKey :HJKBJIYDJLVSAO-UHFFFAOYSA-L
CAS DataBase Reference :22560-50-5(CAS DataBase Reference)
Safety Information
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Description
Clodronate, Disodium Salt is a first-generation bisphosphonate which are synthetic compounds characterized by a P-C-P bond. Experiments have shown that the P-C-P bond of the bisphosphonates is completely resistant to enzymatic hydrolysis. This compound has been reported to inhibit bone resorption and can be metabolized intracellularly to a β,γ-methylene analog of ATP, which in vitro is cytotoxic to macrophages. Additionally, Clodronate demonstrates the ability to cause a collapse of the mitochondrial membrane potential which eventually results in osteoclast apoptosis.More related product prices
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