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Clodronate disodium Salt

Clodronate disodium Salt Structure
CAS No.
22560-50-5
Chemical Name:
Clodronate disodium Salt
Synonyms
DMDP;Loron;CL2MDP;bm06011;U-82067E;lodronate;Difosfonal;clodronatesodium;sodiumclodronate;chlodronatesodium
CBNumber:
CB0318011
Molecular Formula:
CH5Cl2NaO6P2
Molecular Weight:
268.88
MOL File:
22560-50-5.mol
MSDS File:
SDS
Modify Date:
2025/1/27 9:38:02
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Clodronate disodium Salt Properties

Melting point >330°C
storage temp. room temp
solubility Freely soluble in water, practically insoluble in ethanol (96 per cent), slightly soluble in methanol.
form Solid
color White to Off-White
Water Solubility water: 49.00-51.00mg/mL, clear, colorless
InChIKey HJKBJIYDJLVSAO-UHFFFAOYSA-L
CAS DataBase Reference 22560-50-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3
RTECS  SZ7640700
HS Code  29319090
Toxicity mouse,LD50,intraperitoneal,780mg/kg (780mg/kg),British UK Patent Application. Vol. #2096889,

Clodronate disodium Salt price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) D4434 Dichloromethylenediphosphonic acid disodium salt 22560-50-5 1G ₹25168.13 2022-06-14 Buy
Product number Packaging Price Buy
D4434 1G ₹25168.13 Buy

Clodronate disodium Salt Chemical Properties,Uses,Production

Description

Clodronate disodium is a bone resorption inhibitor, useful as adjunct therapy in the treatment of osteolytic bone metastases and malignant hypercalcemia.

Chemical Properties

White Solid

Definition

ChEBI: The disodium salt of clodronic acid. It inhibits bone resorption and soft tissue calcification, and is used (generally as the tetrahydrate) as an adjunct in the treatment of severe hypercalcaemia associated with malignancy, and in the management of osteoly ic lesions and bone pain associated with skeletal metastases.

Hazard

Moderately toxic by ingestion.

Safety Profile

A poison by intravenous route. Moderately toxic by ingestion, intraperitoneal routes. When heated to decomposition it emits toxic vapors of PO, and Cl-

Clodronate disodium Salt Preparation Products And Raw materials

Raw materials

Preparation Products

Clodronate disodium Salt Suppliers

Global( 172)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharmazell Vizag Private Limited 08066085795Ext 308 Andhra Pradesh, India 2 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
XI'AN TIANGUANGYUAN BIOTECH CO., LTD. +86-029-86333380 +86-18829239519 China 898 58 Inquiry
Shanghai Daken Advanced Materials Co.,Ltd +86-371-+86-371-66670886 China 19809 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21628 55 Inquiry
Xiamen AmoyChem Co., Ltd +86-86-5926051114 +8615060885618 China 6383 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49732 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29808 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-29-81139210 +86-18192627656 China 3003 58 Inquiry
Supplier Advantage
Pharmazell Vizag Private Limited 58
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
XI'AN TIANGUANGYUAN BIOTECH CO., LTD. 58
Shanghai Daken Advanced Materials Co.,Ltd 58
Henan Tianfu Chemical Co.,Ltd. 55
Xiamen AmoyChem Co., Ltd 58
CONIER CHEM AND PHARMA LIMITED 58
career henan chemical co 58
Shaanxi Dideu Medichem Co. Ltd 58

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Clodronate disodium Salt
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CL2MDP Phosphonic acid, P,P'-(dichloromethylene)bis-, sodium salt (1:2) Clodronate disodium, >=98% DICHLOROMETHYLENEDIPHOPHONIC ACID DISODIUM SALT DICHLOROMETHYLENEDIPHOSPHONIC ACID DISODIUM SALT DMDP CLODRONIC ACID DISODIUM SALT CLODRONATE DISODIUM (dichloromethylene)bis-phosphonicacidisodiumsalt (dichloromethylene)di-phosphonicacidisodiumsalt bm06011 chlodronatesodium clodronatesodium dichloromethanediphosphonate disodium(dichloromethylene)bisphosphonate disodium [dichloro-[hydroxy(oxido)phosphoryl]methyl]-hydroxy-phosphinate Clodronic Acid, Disodium Salt, Hydrate disodiumclodronate lodronate sodiumclodronate Clodronate Disodium, Bonefos, Clasteon, Clastoban disodium dihydrogen (dichloromethylene)diphosphonate DICHLOROMETHYLENEDIPHOSPHONIC ACID ClodronateAcidDisodiumSalt clodronate disodium，CLD Difosfonal Loron (Dichloromethylene)bis(phosphonic acid hydrogen sodium) salt Disodium crodronate U-82067E disodium [dichloro-[hydroxy(oxidanidyl)phosphoryl]methyl]-hydroxy-phosphinate disodium [dichloro-[hydroxy(oxido)phosphoryl]methyl]-hydroxyphosphinate clodronic acid, sodium salt Cl2MDP, Clodronic acid disodium salt, DMDP (Dichloromethylene)diphosphonate disodium disodium [dichloro(phosphonato)methyl]-dioxido-oxophosphorane clodronicaciddisodiumsal CAS22560-50-5 clodronic acid disodium salt Sodium (dichloro(phosphono)methyl)phosphonate CLODRONATE DISODIUM SALT 22560-50-5 CH2Cl2O6P22Na CH2Cl2Na2O6P2 CH2O6Cl2Na2P2 CH4Cl2O6P02Na Clodronic Acid Disodium Other APIs Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Phosphorylating and Phosphitylating Agents All Inhibitors 22560-50-5