Clodronate disodium
- ₹25168.13
- Product name: Clodronate disodium
- CAS: 22560-50-5
- MF: CH5Cl2NaO6P2
- MW: 268.88
- EINECS:245-078-9
- MDL Number:MFCD01632786
- Synonyms:CL2MDP;Phosphonic acid, P,P'-(dichloromethylene)bis-, sodium salt (1:2);Clodronate disodium, >=98%;DICHLOROMETHYLENEDIPHOPHONIC ACID DISODIUM SALT;DICHLOROMETHYLENEDIPHOSPHONIC ACID DISODIUM SALT;DMDP;CLODRONIC ACID DISODIUM SALT;CLODRONATE DISODIUM
1 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 1G
- ManufacturerSigma-Aldrich(India)
- Product numberD4434
- Product descriptionDichloromethylenediphosphonic acid disodium salt
- Packaging1G
- Price₹25168.13
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | D4434 | Dichloromethylenediphosphonic acid disodium salt | 1G | ₹25168.13 | 2022-06-14 | Buy |
Properties
Melting point :>330°C
storage temp. :room temp
solubility :Freely soluble in water, practically insoluble in ethanol (96 per cent), slightly soluble in methanol.
form :Solid
color :White to Off-White
InChIKey :HJKBJIYDJLVSAO-UHFFFAOYSA-L
CAS DataBase Reference :22560-50-5(CAS DataBase Reference)
storage temp. :room temp
solubility :Freely soluble in water, practically insoluble in ethanol (96 per cent), slightly soluble in methanol.
form :Solid
color :White to Off-White
InChIKey :HJKBJIYDJLVSAO-UHFFFAOYSA-L
CAS DataBase Reference :22560-50-5(CAS DataBase Reference)
Safety Information
Symbol(GHS): | ||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | |||||||||||||||||||||||||||||||||||
Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
Clodronate, Disodium Salt is a first-generation bisphosphonate which are synthetic compounds characterized by a P-C-P bond. Experiments have shown that the P-C-P bond of the bisphosphonates is completely resistant to enzymatic hydrolysis. This compound has been reported to inhibit bone resorption and can be metabolized intracellularly to a β,γ-methylene analog of ATP, which in vitro is cytotoxic to macrophages. Additionally, Clodronate demonstrates the ability to cause a collapse of the mitochondrial membrane potential which eventually results in osteoclast apoptosis.More related product prices
Folic acid Citric acid Disodium pamidronate ACETIC ACID 139-33-3 10163-15-2 Chrysene 22560-50-5Related product price
- Folic acid
₹260-31316.73 - Citric acid
₹270-98042.03 - Disodium pamidronate
₹15280