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ChemicalBook > Product Catalogue >API >Fluid, Electrolyte, and Acid-Base Balance >Acid-base balance regulating drugs >Tris(hydroxymethyl)aminomethane

Tris(hydroxymethyl)aminomethane

Tris(hydroxymethyl)aminomethane Structure
  • ₹810 - ₹644845.25
  • Product name: Tris(hydroxymethyl)aminomethane
  • CAS: 77-86-1
  • MF: C4H11NO3
  • MW: 121.14
  • EINECS:201-064-4
  • MDL Number:MFCD00004679
  • Synonyms:Tromethamine, USP Grade Tris, USP Grade;Tris(hydroxymethyl)aminomethane (TRIS)99.9% ;Tris-hydroxymethylaminomethane: (THAM);TRIS(HYDROXYMETHYL) AMINOMETHANE pure AR;TRIS(HYDROXYMETHYL)AMINOMETHANE extrapure AR;TRIS (HYDROXYMETHYL) AMINO METHANE USP;TRIS(HYDROXYMETHYL)AMINOMETHANE, 99.8+%, A.C.S. REAGENT;TRIZMA(R) BASE, BIOTECHNOLOGY PERFORMANCE CERTIFIED, CELL CULTURE TESTED MEETS EP & USP TESTING SPECIFICATIONS
Price83 Properties Safety Information Description
83 prices
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  • Sigma-Aldrich(India)
  • ALFA India
  • TCI Chemicals (India)
  • Sigma-Aldrich
  • SRL
  • ottokemi

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  • ManufacturerSigma-Aldrich(India)
  • Product numberT1378
  • Product descriptionSigma 7-9® ≥99% (titration), crystalline
  • Packaging500G
  • Price₹7700
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1347
  • Product descriptionTromethamine pharmaceutical secondary standard, certified reference material
  • Packaging1G
  • Price₹8919.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number93352
  • Product descriptionTrizma® base ≥99.0% (T)
  • Packaging500G
  • Price₹9233.73
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT6791
  • Product descriptionTrizma® base BioXtra, pH 10.5-12.0 (1?M in H2O), ≥99.9% (titration)
  • Packaging100G
  • Price₹10056.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT1503
  • Product descriptionTrizma® base Primary Standard and Buffer, ≥99.9% (titration), crystalline
  • Packaging250G
  • Price₹10933.25
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number1.02408
  • Product descriptionTris(hydroxymethyl)aminomethane volumetric standard, secondary reference material for acidimetry, traceable to NIST Standard Reference Material (SRM) Certipur? Reag. Ph Eur,Reag. USP
  • Packaging80G
  • Price₹11480
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT6687
  • Product descriptionTromethamine meets USP testing specifications
  • Packaging100G
  • Price₹4490
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number252859
  • Product descriptionTris(hydroxymethyl)aminomethane ACS reagent, ≥99.8%
  • Packaging500G
  • Price₹5090
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT1503
  • Product descriptionTrizma® base Primary Standard and Buffer, ≥99.9% (titration), crystalline
  • Packaging100G
  • Price₹5185.18
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT6066
  • Product descriptionTrizma® base BioPerformance Certified, meets EP, USP testing specifications, suitable for cell culture, ≥99.9% (titration)
  • Packaging100G
  • Price₹5412.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT4661
  • Product descriptionTrizma® base ≥99.9% (titration), crystalline
  • Packaging100G
  • Price₹5856.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT6066
  • Product descriptionTrizma® base BioPerformance Certified, meets EP, USP testing specifications, suitable for cell culture, ≥99.9% (titration)
  • Packaging500G
  • Price₹6473.35
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberRDD008
  • Product descriptionTrizma® base anhydrous, free-flowing, Redi-Dri?, ≥99.9%
  • Packaging1KG
  • Price₹18121.05
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number93352
  • Product descriptionTrizma® base ≥99.0% (T)
  • Packaging1KG
  • Price₹15133.35
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number93350
  • Product descriptionTrizma® base puriss. p.a., ≥99.7% (T)
  • Packaging500G
  • Price₹14180.75
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT1378
  • Product descriptionSigma 7-9® ≥99% (titration), crystalline
  • Packaging1KG
  • Price₹13270
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) T1378 Sigma 7-9® ≥99% (titration), crystalline 500G ₹7700 2022-06-14 Buy
Sigma-Aldrich(India) PHR1347 Tromethamine pharmaceutical secondary standard, certified reference material 1G ₹8919.8 2022-06-14 Buy
Sigma-Aldrich(India) 93352 Trizma® base ≥99.0% (T) 500G ₹9233.73 2022-06-14 Buy
Sigma-Aldrich(India) T6791 Trizma® base BioXtra, pH 10.5-12.0 (1?M in H2O), ≥99.9% (titration) 100G ₹10056.43 2022-06-14 Buy
Sigma-Aldrich(India) T1503 Trizma® base Primary Standard and Buffer, ≥99.9% (titration), crystalline 250G ₹10933.25 2022-06-14 Buy
Sigma-Aldrich(India) 1.02408 Tris(hydroxymethyl)aminomethane volumetric standard, secondary reference material for acidimetry, traceable to NIST Standard Reference Material (SRM) Certipur? Reag. Ph Eur,Reag. USP 80G ₹11480 2022-06-14 Buy
Sigma-Aldrich(India) T6687 Tromethamine meets USP testing specifications 100G ₹4490 2022-06-14 Buy
Sigma-Aldrich(India) 252859 Tris(hydroxymethyl)aminomethane ACS reagent, ≥99.8% 500G ₹5090 2022-06-14 Buy
Sigma-Aldrich(India) T1503 Trizma® base Primary Standard and Buffer, ≥99.9% (titration), crystalline 100G ₹5185.18 2022-06-14 Buy
Sigma-Aldrich(India) T6066 Trizma® base BioPerformance Certified, meets EP, USP testing specifications, suitable for cell culture, ≥99.9% (titration) 100G ₹5412.5 2022-06-14 Buy
Sigma-Aldrich(India) T4661 Trizma® base ≥99.9% (titration), crystalline 100G ₹5856.33 2022-06-14 Buy
Sigma-Aldrich(India) T6066 Trizma® base BioPerformance Certified, meets EP, USP testing specifications, suitable for cell culture, ≥99.9% (titration) 500G ₹6473.35 2022-06-14 Buy
Sigma-Aldrich(India) RDD008 Trizma® base anhydrous, free-flowing, Redi-Dri?, ≥99.9% 1KG ₹18121.05 2022-06-14 Buy
Sigma-Aldrich(India) 93352 Trizma® base ≥99.0% (T) 1KG ₹15133.35 2022-06-14 Buy
Sigma-Aldrich(India) 93350 Trizma® base puriss. p.a., ≥99.7% (T) 500G ₹14180.75 2022-06-14 Buy
Sigma-Aldrich(India) T1378 Sigma 7-9® ≥99% (titration), crystalline 1KG ₹13270 2022-06-14 Buy
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Properties

Melting point :167-172 °C(lit.)
Boiling point :219-220 °C10 mm Hg(lit.)
Density :1,353 g/cm3
vapor pressure :0.0267 hPa (20 °C)
refractive index :1.4170 (estimate)
Flash point :219-220°C/10mm
storage temp. :20-25°C
solubility :H2O: 4 M at 20 °C, clear, colorless
form :crystalline
color :white
PH Range :7 - 9
PH :10.5-12.0(4 m in water, 25 °C)
pka :8.1(at 25℃)
Water Solubility :550 g/L (25 ºC)
λmax :λ: 260 nm Amax: 0.10
λ: 280 nm Amax: 0.08 Sensitive :Hygroscopic
Merck :14,9772
BRN :741883
Stability :Stable. Incompatible with bases, strong oxidizing agents. Protect from moisture.
InChIKey :LENZDBCJOHFCAS-UHFFFAOYSA-N
LogP :-2.515 (est)
CAS DataBase Reference :77-86-1(CAS DataBase Reference)
NIST Chemistry Reference :1,3-Propanediol, 2-amino-2-(hydroxymethyl)-(77-86-1)
EPA Substance Registry System :Tris(hydroxymethyl)aminomethane (77-86-1)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

TRIS-buffered saline (TBS, 10X) pH 7.6 is used as a substance diluent, as a wash buffer in immunoassays such as enzyme-linked immunosorbent assay. It is used in antibody diluent in western blotting, sample diluent in vitro diagnostics, immuno-histochemical staining and in situ hybridization.

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