H-SER-LEU-ILE-GLY-ARG-LEU-NH2
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- ₹10803.35
- Product name: H-SER-LEU-ILE-GLY-ARG-LEU-NH2
- CAS: 171436-38-7
- MF: C29H56N10O7
- MW: 656.82
- EINECS:
- MDL Number:MFCD03093421
- Synonyms:COAGULATION FACTOR II RECEPTOR-LIKE 1 (1-6) AMIDE (MOUSE, RAT);H-SER-LEU-ILE-GLY-ARG-LEU-NH2;H2N-SLIGRL-AMIDE;Ser-Leu-Ile-Gly-Arg-Leu-NH2;SLIGRL-NH2 Protease-Activated Receptor 2 (PAR2) Agonist;PAR2-AP, SLIGRL-NH2;Ser-Leu-Ile-Gly-Arg-Leu-amide trifluoroacetate salt;ThroMbin Receptor-Like 1 (1-6) aMide (Mouse, rat), SLIGRLaMide, Proteinase Activated Receptor 2 (1-6) aMide (Mouse, rat), Coagulation Factor II Receptor-Like 1 (1-6) aMide (Mouse, rat)
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- ManufacturerSigma-Aldrich(India)
- Product numberS9317
- Product descriptionPAR-2 (1-6) amide (mouse, rat) trifluoroacetate salt ≥97% (HPLC)
- Packaging1MG
- Price₹10803.35
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | S9317 | PAR-2 (1-6) amide (mouse, rat) trifluoroacetate salt ≥97% (HPLC) | 1MG | ₹10803.35 | 2022-06-14 | Buy |
Properties
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form :solid
pka :12.04±0.10(Predicted)
color :White to off-white
Water Solubility :Soluble to 1 mg/ml in water
storage temp. :-20°C
solubility :DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form :solid
pka :12.04±0.10(Predicted)
color :White to off-white
Water Solubility :Soluble to 1 mg/ml in water
Safety Information
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Description
Proteinase-activated receptor 2 (PAR2) is a G protein-coupled receptor that is cleaved by serine proteases, resulting in self-activation of the receptor by a tethered ligand. The ligand corresponds to residues 39-44 (SLIGRL in mouse PAR-2). SLIGRL-NH2 is a recombinant peptide that activates PAR2 (EC50 = ~5 μM), without requiring receptor cleavage. This peptide does not activate PAR1. Through its effects on PAR2, SLIGRL-NH2 stimulates gastric and intestinal smooth muscle contraction and induces thermal hyperalgesia in mice. SLIGRL-NH2 is used to explore signaling through PAR2 in cells and in animals.Related product price
- H-SER-LEU-ILE-GLY-ARG-LEU-NH2
₹10803.35
