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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Fluoropyrimidine >Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate

Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate

Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate Structure
  • ₹6873.88
  • Product name: Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate
  • CAS: 175137-27-6
  • MF: C7H4ClF3N2O2
  • MW: 240.57
  • EINECS:
  • MDL Number:MFCD00068146
  • Synonyms:BUTTPARK 46\18-97;METHYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE;Methyl2-chloro-4-(trifluoromethyl)pyrimidine-5- ;Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-;Methyl 2-Chloro-4-(trif1uoromethyl) pyridine-5-carboxylate;Methyl 2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxylate;2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic acid methyl ester;Methyl-2-chloro-4-(trifluoromethyl)pyrimidin-5-carboxylate
Price1 Properties Safety Information Description
1 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product number714372
  • Product descriptionMethyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate 97%
  • Packaging1G
  • Price₹6873.88
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 714372 Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate 97% 1G ₹6873.88 2022-06-14 Buy

Properties

Melting point :253-254 °C
Boiling point :76-78°C 0,5mm
Density :1.491
refractive index :n20/D1.468
Flash point :>110℃
storage temp. :2-8°C
pka :-5.70±0.29(Predicted)
CAS DataBase Reference :175137-27-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Methyl 2-Chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate is used in the synthetic preparation and discovery of 2-[(2,4-Dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide (G931520) which is a highly selective CB2 receptor agonist for the treatment of inflammatory and neuropathic pain.

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Related product price

Suppliers and manufacturers

career henan chemical co
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate
₹1.00 /1KG
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate CAS:175137-27-6
Shaanxi Dideu Medichem Co. Ltd
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate
₹1.10 /1g
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate CAS:175137-27-6
Dideu Industries Group Limited
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate
₹1.10 /1g
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate CAS:175137-27-6
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