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N-(CYCLOPROPYLMETHOXY)-3,4,5-TRIFLUORO-2-[(4-IODO-2-METHYLPHENYL)AMINO]-BENZAMIDE

N-(CYCLOPROPYLMETHOXY)-3,4,5-TRIFLUORO-2-[(4-IODO-2-METHYLPHENYL)AMINO]-BENZAMIDE Structure
  • ₹20250
  • Product name: N-(CYCLOPROPYLMETHOXY)-3,4,5-TRIFLUORO-2-[(4-IODO-2-METHYLPHENYL)AMINO]-BENZAMIDE
  • CAS: 212631-61-3
  • MF: C18H16F3IN2O2
  • MW: 476.23
  • EINECS:
  • MDL Number:MFCD08690428
  • Synonyms:N-(CYCLOPROPYLMETHOXY)-3,4,5-TRIFLUORO-2-[(4-IODO-2-METHYLPHENYL)AMINO]-BENZAMIDE;PD 198306;N-(cyclopropylmethoxy)-3,4,5-trifluoro-2-(4-iodo-2-methylanilino)benzamide;Benzamide, N-(cyclopropylmethoxy)-3,4,5-trifluoro-2-[(4-iodo-2-methylphenyl)amino]-;MAPK,inhibit,neuropathic,Inhibitor,MAP2K,rabies,mitogen-activated protein,drug,MAPKK,PD-198306,phosphatases,PD 198306,inositol,RNA,pain,interference,MEK,ERK,antihyperalgesic,screening,Mitogen-activated protein kinase kinase,phosphate,kinases,PD198306;PD 198306, 10 mM in DMSO;MEK Inhibitor VIII
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product number444965
  • Product descriptionMEK Inhibitor VIII - CAS 212631-61-3 - Calbiochem The MEK1/2 Inhibitor II, also referenced under CAS 212631-61-3, controls the biological activity of MEK1/2. This small molecule/inhibitor is primarily
  • Packaging5MG
  • Price₹20250
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 444965 MEK Inhibitor VIII - CAS 212631-61-3 - Calbiochem The MEK1/2 Inhibitor II, also referenced under CAS 212631-61-3, controls the biological activity of MEK1/2. This small molecule/inhibitor is primarily 5MG ₹20250 2022-06-14 Buy

Properties

Melting point :125-127 °C
Density :1.686±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :Soluble in DMSO
form :solid
pka :-3.95±0.50(Predicted)
color :White

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

PD 198306 is a cell-permeable amino-benzamide compound that acts as a potent and non-ATP-competitive inhibitor of MEK1/2 (IC50 = 8 nM) with an excellent selectivity over ERK, c-Src, Cdk's, and PI 3-Kγ (IC50 >1.0 μM).

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