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1400 W DIHYDROCHLORIDE, 96

1400 W DIHYDROCHLORIDE, 96 Structure
  • ₹17860 - ₹18229.3
  • Product name: 1400 W DIHYDROCHLORIDE, 96
  • CAS: 214358-33-5
  • MF: C8H11NO
  • MW: 137.17904
  • EINECS:
  • MDL Number:MFCD03428622
  • Synonyms:1400W (hydrochloride);N-(3-(aMinoMethyl)benzyl)acetiMidaMide dihydrochloride;N-[3-(AMinoMethyl)benzyl]ethaniMidaMide dihydrochloride;1400 W DIHYDROCHLORIDE, 96;1400W2HCl;1400W - CAS 214358-33-5 - Calbiochem;inhibit,1400W dihydrochloride,NO Synthase,NOS,Nitric oxide synthases,1400W,Inhibitor
2 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • ManufacturerSigma-Aldrich(India)
  • Product number100050
  • Product description1400W - CAS 214358-33-5 - Calbiochem A selective, cell-permeable, irreversible, slow, tight-binding inhibitor of inducible nitric oxide synthase (iNOS; Kd = 7 nM).
  • Packaging5MG
  • Price₹17860
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberW4262
  • Product description1400W dihydrochloride >98%, solid
  • Packaging10MG
  • Price₹18229.3
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 100050 1400W - CAS 214358-33-5 - Calbiochem A selective, cell-permeable, irreversible, slow, tight-binding inhibitor of inducible nitric oxide synthase (iNOS; Kd = 7 nM). 5MG ₹17860 2022-06-14 Buy
Sigma-Aldrich(India) W4262 1400W dihydrochloride >98%, solid 10MG ₹18229.3 2022-06-14 Buy

Properties

Melting point :208 °C
storage temp. :-20°C
solubility :Soluble in Water (up to 25 mg/ml).
form :White solid
color :White
Water Solubility :Soluble to 100 mM in water
Stability :Stable for 1 year as supplied. Solutions are not stable. Solutions must be prepared fresh and used within one working day.

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

1400W is a potent, selective inhibitor of iNOS. Using purified human iNOS, nNOS, and eNOS, 1400W exhibits Ki values of 7 nM, 2 μM, and 50 μM, respectively. In rat aortic rings it is at least 1,000-fold more potent against iNOS compared to eNOS. In mice bearing a murine mammary carcinoma, continuous infusion of 1400W at a rate of 10 mg/kg for 6 days decreased tumor weight approximately 50% compared to controls.

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