1,4-PBIT DIHYDROBROMIDE
- ₹0
- Product name: 1,4-PBIT DIHYDROBROMIDE
- CAS: 157254-60-9
- MF: C12H20Br2N4S2
- MW: 444.25
- EINECS:
- MDL Number:MFCD00797677
- Synonyms:S,S'-(1,4-PHENYLENE-BIS(1,2-ETHANEDIYL))BIS-ISOTHIOUREA DIHYDROBROMIDE;1,4-Phenylene-bis(1,2-ethanediyl)bis-isothiourea dihydrobromide;YRRYHMLYGVNPBW-UHFFFAOYSA-N;1,4-PBIT DIHYDROBROMIDE;1,4-PB-ITU DIHYDROBROMIDE;PBIT (dihydrobromide);Carbamimidothioic acid, C,C'-(1,4-phenylenedi-2,1-ethanediyl) ester, hydrobromide (1:2)
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Properties
Melting point :234-236 °C
storage temp. :−20°C
solubility :DMF: 20 mg/ml; DMSO: 25 mg/ml; PBS (pH 7.2): 5 mg/ml
form :White to off-white powder.
storage temp. :−20°C
solubility :DMF: 20 mg/ml; DMSO: 25 mg/ml; PBS (pH 7.2): 5 mg/ml
form :White to off-white powder.
Safety Information
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Description
1,4-PBIT is a potent inhibitor of purified human iNOS and nNOS with Ki values of 7.4 and 16 nM, respectively, compared to a Ki of 360 nM for human eNOS. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.More related product prices
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