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AMINO[(3,4-DICHLOROBENZYL)SULFANYL]METHANIMINIUM CHLORIDE

AMINO[(3,4-DICHLOROBENZYL)SULFANYL]METHANIMINIUM CHLORIDE Structure
  • ₹9190.43 - ₹37173.05
  • Product name: AMINO[(3,4-DICHLOROBENZYL)SULFANYL]METHANIMINIUM CHLORIDE
  • CAS: 22816-60-0
  • MF: C8H9Cl3N2S
  • MW: 271.59
  • EINECS:
  • MDL Number:MFCD00035050
  • Synonyms:AMINO[(3,4-DICHLOROBENZYL)SULFANYL]METHANIMINIUM CHLORIDE;[AMINO[(3,4-DICHLOROBENZYL)THIO]METHYLIDENE]AMMONIUM CHLORIDE;2-(3,4-Dichloro-benzyl)-isothiourea hydrochloride;2-(3,4-dichlorophenyl)methylcarbamimidothioate hydrochloride;A22 hydrochloride;MreB Perturbing Compound A22;S-(3,4-Dichlorobenzyl)isothiourea hydrochloride;Carbamimidothioic acid,(3,4-dichlorophenyl)methyl ester, hydrochloride (1:1)
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 25MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0471
  • Product descriptionA22 hydrochloride ≥95% (HPLC)
  • Packaging10MG
  • Price₹9190.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number475951
  • Product descriptionMreB Perturbing Compound A22 - CAS 22816-60-0 - Calbiochem A cell-permeable isothiourea compound that specifically, rapidly and reversibly perturbs MreB function without affecting eukaryotic actin polymerizati
  • Packaging25MG
  • Price₹12940
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0471
  • Product descriptionA22 hydrochloride ≥95% (HPLC)
  • Packaging50MG
  • Price₹37173.05
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0471 A22 hydrochloride ≥95% (HPLC) 10MG ₹9190.43 2022-06-14 Buy
Sigma-Aldrich(India) 475951 MreB Perturbing Compound A22 - CAS 22816-60-0 - Calbiochem A cell-permeable isothiourea compound that specifically, rapidly and reversibly perturbs MreB function without affecting eukaryotic actin polymerizati 25MG ₹12940 2022-06-14 Buy
Sigma-Aldrich(India) SML0471 A22 hydrochloride ≥95% (HPLC) 50MG ₹37173.05 2022-06-14 Buy

Properties

Melting point :210 °C
storage temp. :2-8°C
solubility :H2O: soluble2mg/mL (clear solution, warmed)
form :White solid
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

MreB is an actin-like protein expressed in bacteria. It determines the rod shape of cells and has critical roles in cell division, chromosome segregation, and cell polarity. MreB perturbing compound A22 is a benzylisothiourea compound that interacts with the ATP binding site of MreB rapidly and reversibly. It blocks normal rod shape formation and inhibits chromosome partitioning in E. coli, inhibiting growth (MIC = 3.1 μg/ml). It interferes with chromosome segregation in C. crescentus by preventing MreB binding to chromosomes. In V. cholerae, A22 prevents the development of normal cell shape and alters nucleoid morphology.

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