5-(1-Hydroxy-2-tert-butylamino-ethyl)benzene-1,3-diol
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- Product name: 5-(1-Hydroxy-2-tert-butylamino-ethyl)benzene-1,3-diol
- CAS: 23031-25-6
- MF: C12H19NO3
- MW: 225.28
- EINECS:245-385-8
- MDL Number:
- Synonyms:5-(1-Hydroxy-2-tert-butylamino-ethyl)benzene-1,3-diol;(R)-α-[(tert-Butylamino)methyl]-3,5-dihydroxybenzyl alcohol;(S)-α-[(tert-Butylamino)methyl]-3,5-dihydroxybenzyl alcohol;5-[(S)-1-Hydroxy-2-(tert-butylamino)ethyl]benzene-1,3-diol;rac-5-[(R*)-2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-1,3-benzenediol;C07129;Terbutaline & Terbutaline Sulfate;Terbutaline-d3
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Properties
Melting point :119-122°
Boiling point :366.8°C (rough estimate)
Density :1.0951 (rough estimate)
refractive index :1.4596 (estimate)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :pKa 8.70(H2O t = 25 I = 0.01) (Uncertain);10.09(H2O t = 25 I = 0.01) (Uncertain)
color :White to Off-White
CAS DataBase Reference :23031-25-6
Boiling point :366.8°C (rough estimate)
Density :1.0951 (rough estimate)
refractive index :1.4596 (estimate)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :pKa 8.70(H2O t = 25 I = 0.01) (Uncertain);10.09(H2O t = 25 I = 0.01) (Uncertain)
color :White to Off-White
CAS DataBase Reference :23031-25-6
Safety Information
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Description
Terbutaline is a synthetic congener of adrenaline that acts at the β2-receptor causing bronchodilation and tocolytic effects. It was the first β2-selective adrenoreceptor agonist in general clinical use. In 2011, the Food and Drug Administration (FDA) placed a black-boxed warning on terbutaline stating that terbutaline injections should not be given to pregnant women nor should be used to prevent preterm labor or for long-term (greater than 48–72 h) treatment of preterm labor. Oral terbutaline should not be used at all due to its potential for cardiac toxicity and death. Terbutaline is on the World Anti- Doping Agency’s list of prohibited drugs for Olympic athletes (except when a Therapeutic Use Exemption has been granted in advance and when used by inhalation).Related product price
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Suppliers and manufacturers
Venkatasai Life Sciences
CLEARSYNTH LABS LTD.
SynZeal Research Pvt Ltd
Pharmaffiliates Analytics and Synthetics P. Ltd
Lexine Technochem Private Limited
Pharma Affiliates
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Hefei TNJ Chemical Industry Co.,Ltd.
