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ChemicalBook > Product Catalogue >Chemical Reagents >Silane reagent >N-Methyl-N-(trimethylsilyl)trifluoroacetamide

N-Methyl-N-(trimethylsilyl)trifluoroacetamide

N-Methyl-N-(trimethylsilyl)trifluoroacetamide Structure
  • ₹1790 - ₹54854
  • Product name: N-Methyl-N-(trimethylsilyl)trifluoroacetamide
  • CAS: 24589-78-4
  • MF: C6H12F3NOSi
  • MW: 199.25
  • EINECS:246-331-6
  • MDL Number:MFCD00000411
  • Synonyms:N-METHYL-N-(TRIMETHYLSILYL)TRIFLUOROACETAMIDE W. 1% TMCS;N-METHYL-N-(TRIMETHYLSILYL)TRIFLUORO-ACE TAMIDE, DERIVATIZATION GRADE;N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACET-A MIDE, FOR GC;N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACETAM, 10x1ML PACKSIZE;N-METHYL-N-(TRIMETHYLSILYL)TRIFLUOROACETAMIDE 98%;N-Methyl-N-(Trimethylsily)Trifluoroacetamide;N-Methyl-N-(trimethylsilyl)trifluoroacetamide, 98;MSTFA~N-Trimethylsilyl-N-methyltrifluoroacetamide
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ALFA India
  • SRL

Package

  • 1ML
  • 10X0.1ML
  • 2ML
  • 5G
  • 5ML
  • 10X1ML
  • 10X1.2ML
  • 25G
  • 25ML
  • 100mL
  • 100g
  • ManufacturerTCI Chemicals (India)
  • Product numberM0672
  • Product descriptionN-Methyl-N-trimethylsilyltrifluoroacetamide [Trimethylsilylating Agent] min. 95.0 %
  • Packaging5ML
  • Price₹2900
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM0672
  • Product descriptionN-Methyl-N-trimethylsilyltrifluoroacetamide [Trimethylsilylating Agent] min. 95.0 %
  • Packaging25ML
  • Price₹6600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number8.41102
  • Product descriptionN-Methyl-N-trimethylsilyl-trifluoroacetamide for synthesis
  • Packaging5ML
  • Price₹1790
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number8.41102
  • Product descriptionN-Methyl-N-trimethylsilyl-trifluoroacetamide for synthesis
  • Packaging2ML
  • Price₹1970
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM7891
  • Product descriptionN-Methyl-N-(trimethylsilyl)trifluoroacetamide BioReagent, for silylations, LiChropur?
  • Packaging1ML
  • Price₹4524.85
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number69478
  • Product descriptionN-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane for GC derivatization, LiChropur?
  • Packaging1ML
  • Price₹4721.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM7891
  • Product descriptionN-Methyl-N-(trimethylsilyl)trifluoroacetamide BioReagent, for silylations, LiChropur?
  • Packaging5G
  • Price₹5152.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number8.41102
  • Product descriptionN-Methyl-N-trimethylsilyl-trifluoroacetamide for synthesis
  • Packaging25ML
  • Price₹6750.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number394866
  • Product descriptionN-Methyl-N-(trimethylsilyl)trifluoroacetamide synthesis grade
  • Packaging25ML
  • Price₹36999.85
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM7891
  • Product descriptionN-Methyl-N-(trimethylsilyl)trifluoroacetamide BioReagent, for silylations, LiChropur?
  • Packaging10X1ML
  • Price₹18748.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number69478
  • Product descriptionN-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane for GC derivatization, LiChropur?
  • Packaging10X1ML
  • Price₹18806.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number1.11805
  • Product description2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide for gas chromatography
  • Packaging5ML
  • Price₹21240
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number69478
  • Product descriptionN-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane for GC derivatization, LiChropur?
  • Packaging5ML
  • Price₹21878.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number69478
  • Product descriptionN-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane for GC derivatization, LiChropur?
  • Packaging10X0.1ML
  • Price₹22676.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number69479
  • Product descriptionN-Methyl-N-(trimethylsilyl)trifluoroacetamide for GC derivatization, LiChropur?, ≥98.5%
  • Packaging25ML
  • Price₹36945.73
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number69479
  • Product descriptionN-Methyl-N-(trimethylsilyl)trifluoroacetamide for GC derivatization, LiChropur?, ≥98.5%
  • Packaging5ML
  • Price₹8757.43
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) M0672 N-Methyl-N-trimethylsilyltrifluoroacetamide [Trimethylsilylating Agent] min. 95.0 % 5ML ₹2900 2022-05-26 Buy
TCI Chemicals (India) M0672 N-Methyl-N-trimethylsilyltrifluoroacetamide [Trimethylsilylating Agent] min. 95.0 % 25ML ₹6600 2022-05-26 Buy
Sigma-Aldrich(India) 8.41102 N-Methyl-N-trimethylsilyl-trifluoroacetamide for synthesis 5ML ₹1790 2022-06-14 Buy
Sigma-Aldrich(India) 8.41102 N-Methyl-N-trimethylsilyl-trifluoroacetamide for synthesis 2ML ₹1970 2022-06-14 Buy
Sigma-Aldrich(India) M7891 N-Methyl-N-(trimethylsilyl)trifluoroacetamide BioReagent, for silylations, LiChropur? 1ML ₹4524.85 2022-06-14 Buy
Sigma-Aldrich(India) 69478 N-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane for GC derivatization, LiChropur? 1ML ₹4721.5 2022-06-14 Buy
Sigma-Aldrich(India) M7891 N-Methyl-N-(trimethylsilyl)trifluoroacetamide BioReagent, for silylations, LiChropur? 5G ₹5152.7 2022-06-14 Buy
Sigma-Aldrich(India) 8.41102 N-Methyl-N-trimethylsilyl-trifluoroacetamide for synthesis 25ML ₹6750.01 2022-06-14 Buy
Sigma-Aldrich(India) 394866 N-Methyl-N-(trimethylsilyl)trifluoroacetamide synthesis grade 25ML ₹36999.85 2022-06-14 Buy
Sigma-Aldrich(India) M7891 N-Methyl-N-(trimethylsilyl)trifluoroacetamide BioReagent, for silylations, LiChropur? 10X1ML ₹18748.9 2022-06-14 Buy
Sigma-Aldrich(India) 69478 N-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane for GC derivatization, LiChropur? 10X1ML ₹18806.2 2022-06-14 Buy
Sigma-Aldrich(India) 1.11805 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide for gas chromatography 5ML ₹21240 2022-06-14 Buy
Sigma-Aldrich(India) 69478 N-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane for GC derivatization, LiChropur? 5ML ₹21878.5 2022-06-14 Buy
Sigma-Aldrich(India) 69478 N-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane for GC derivatization, LiChropur? 10X0.1ML ₹22676.5 2022-06-14 Buy
Sigma-Aldrich(India) 69479 N-Methyl-N-(trimethylsilyl)trifluoroacetamide for GC derivatization, LiChropur?, ≥98.5% 25ML ₹36945.73 2022-06-14 Buy
Sigma-Aldrich(India) 69479 N-Methyl-N-(trimethylsilyl)trifluoroacetamide for GC derivatization, LiChropur?, ≥98.5% 5ML ₹8757.43 2022-06-14 Buy

Properties

Melting point :98-100°C
Boiling point :130132°C
Density :1.075 g/mL at 25 °C(lit.)
vapor density :>1 (vs air)
vapor pressure :8.8 mm Hg ( 27 °C)
refractive index :n20/D 1.383
Flash point :77 °F
storage temp. :2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
pka :-1.34±0.70(Predicted)
form :Liquid
color :Clear colorless to light yellow
Specific Gravity :1.076
Water Solubility :reacts
Sensitive :Moisture Sensitive
Hydrolytic Sensitivity :7: reacts slowly with moisture/water
BRN :1941550
InChIKey :MSPCIZMDDUQPGJ-UHFFFAOYSA-N
CAS DataBase Reference :24589-78-4(CAS DataBase Reference)
EPA Substance Registry System :Acetamide, 2,2,2-trifluoro-N-methyl-N-(trimethylsilyl)- (24589-78-4)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.

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