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ChemicalBook > Product Catalogue >Organic Chemistry >Amides >Acyclic polyamines and their derivatives >2,6-Dioxopiperidine-3-ammonium chloride

2,6-Dioxopiperidine-3-ammonium chloride

2,6-Dioxopiperidine-3-ammonium chloride Structure
  • ₹0
  • Product name: 2,6-Dioxopiperidine-3-ammonium chloride
  • CAS: 24666-56-6
  • MF: C5H9ClN2O2
  • MW: 164.59016
  • EINECS:807-866-6
  • MDL Number:MFCD11042437
  • Synonyms:2,6-Dioxopiperidine-3-ammonium chloride;2,6-Dioxopiperidine-3-ammonium;Lenalidomide Impurity 6 HCl;Pomalidomide/lenalidomide INT II;3-Amino-piperidine-2,6-dione [2353-44-8] at 262 USD, please be noted, what we provide is HCl salt form;2,6-dioxopiperidin-3-aminium chloride;Pomalidomide Impurity 6;6-piperidinedione hydrochloride
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :120 °C (approx)
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO (Slightly, Heated), Methanol (Sparingly, Sonicated)
form :powder
color :White
InChI :InChI=1S/C5H8N2O2.ClH/c6-3-1-2-4(8)7-5(3)9;/h3H,1-2,6H2,(H,7,8,9);1H
InChIKey :YCPULGHBTPQLRH-UHFFFAOYSA-N
SMILES :C1CC(N)C(=O)NC1=O.Cl

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

2,6-Dioxopiperidine-3-ammonium chloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del (5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation. Moreover, it is also a metabolite of thalidomide (T338850) that inhibits FGF-induced angiogenesis.

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Suppliers and manufacturers

TYNDAL LABS PVT LTD VGS SYNTHESIS PRIVATE LIMITED GLP Pharma Standards TAGOOR LABORATORIES PVT LTD Kalam Sai Life Sciences Pvt Ltd Acura Life Sciences RVR Labs Pvt Ltd VASISTA LIFE SCIENCES PRIVATE LIMITED Aastrid Life Sciences Private Limited Molkem Chemicals