N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE
- ₹22650
- Product name: N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE
- CAS: 269390-69-4
- MF: C19H16ClN3O
- MW: 337.8
- EINECS:
- MDL Number:MFCD09037563
- Synonyms:VEGFR Tyrosine Kinase Inhibitor II;N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE;VEGF RECEPTOR TYROSINE KINASE INHIBITOR II;Valatinib;Benzamide, N-(4-chlorophenyl)-2-[(4-pyridinylmethyl)amino]-;VEGFR-IN-1;VEGFR Tyrosine Kinase;VEGFR IN 1,VEGFRIN1
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Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product number676481
- Product descriptionVEGFR Tyrosine Kinase Inhibitor II - CAS 269390-69-4 - Calbiochem The VEGFR Tyrosine Kinase Inhibitor II, also referenced under CAS 269390-69-4, controls the biological activity of VEGFR Tyrosine Kinase. This small m
- Packaging5MG
- Price₹22650
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 676481 | VEGFR Tyrosine Kinase Inhibitor II - CAS 269390-69-4 - Calbiochem The VEGFR Tyrosine Kinase Inhibitor II, also referenced under CAS 269390-69-4, controls the biological activity of VEGFR Tyrosine Kinase. This small m | 5MG | ₹22650 | 2022-06-14 | Buy |
Properties
Boiling point :463.6±40.0 °C(Predicted)
Density :1.331±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 25 mg/ml
form :A crystalline solid
pka :12.62±0.70(Predicted)
color :White to off-white
Density :1.331±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 25 mg/ml
form :A crystalline solid
pka :12.62±0.70(Predicted)
color :White to off-white
Safety Information
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Description
VEGFR tyrosine kinase inhibitor II is a pyridinyl-anthranilamide compound that inhibits the kinase activities of VEGFR2 (KDR), VEGFR1 (FLT1), and c-Kit (IC50s = 20, 180, and 240 nM, respectively). It displays minimal activity against c-Src and EGFR (IC50s = 7 and 7.3 μM, respectively) and is inactive against Cdk1, c-Met, IGF-1R, and PKA (IC50s > 10 μM). VEGFR tyrosine kinase inhibitor II has been investigated for its potential to inhibit tumor induced angiogenesis.More related product prices
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- 269390-69-4
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