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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >2-Carboxybenzoyl Amlodipine

2-Carboxybenzoyl Amlodipine

2-Carboxybenzoyl Amlodipine Structure
  • ₹0
  • Product name: 2-Carboxybenzoyl Amlodipine
  • CAS: 318465-73-5
  • MF: C28H29ClN2O8
  • MW: 556.99
  • EINECS:608-671-7
  • MDL Number:MFCD21363416
  • Synonyms:Amlodipine EP Impurity I;2-(2-((4-(2-Chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridin-2;2-Carboxybenzoyl Amlodipine;2-[[2-[[(4RS)-4-(2-Chlorophenyl)-3-(ethoxycarbonyl)- 5-(Methoxycarbonyl)-6-Methyl-1,4-dihydropyridin-2-yl] Methoxy]ethyl]-carbaMoyl]benzoic Acid;2-[[2-[(2-Carboxybenzoyl)aMino]ethoxy]Methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-Methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester;2-(2-((4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(Methoxycarbonyl)-6-Methyl-1,4-dihydropyridin-2-yl)Methoxy)ethylcarbaMoyl)benzoic acid;AMlodipine IMpurity H (EP);AMlodipine EP IMpurity H
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :160-162°C
Boiling point :727.6±60.0 °C(Predicted)
Density :1.305±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
pka :3.49±0.36(Predicted)
form :Solid
color :White to Off-White
PH :4.94 at 27.1℃ and 1000g/L
LogP :23 at 25℃

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H402 Harmful to aquatic life Hazardous to the aquatic environment, acute hazard Category 3
H412 Harmful to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 3 P273, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P314 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to..…

Description

As Amlodipine Besilate (A633500) impurity, 2-Carboxybenzoyl AMlodipine can be used in the process for preparing Amlodipine benzenesulfonate.