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ChemicalBook > Product Catalogue >Biochemical Engineering >Nucleoside drugs >Nucleotides and their analogs >METHYL PHOSPHORODICHLORIDITE

METHYL PHOSPHORODICHLORIDITE

METHYL PHOSPHORODICHLORIDITE Structure
  • ₹7500 - ₹33286.88
  • Product name: METHYL PHOSPHORODICHLORIDITE
  • CAS: 3279-26-3
  • MF: CH3Cl2OP
  • MW: 132.91
  • EINECS:221-915-3
  • MDL Number:MFCD00000524
  • Synonyms:METHYL DICHLOROPHOSPHITE, TECHNICAL GRADE;O-Methyl Phosphorodichloridite;Methoxydichlorophosphine;Methoxyphosphonous Dichloride;O-Methyl Phosphorodichloridit;Methyl Dichlorophosphite [Phosphitylating Agent];Methyl dichlorophosphite,98%;Methyl dichlorophosphite, 98% 5ML
3 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10G
  • 50G
  • ManufacturerTCI Chemicals (India)
  • Product numberM0905
  • Product descriptionMethyl Dichlorophosphite [Phosphitylating Agent]
  • Packaging10G
  • Price₹7500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number235229
  • Product descriptionMethyl dichlorophosphite technical grade
  • Packaging10G
  • Price₹9937.35
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number235229
  • Product descriptionMethyl dichlorophosphite technical grade
  • Packaging50G
  • Price₹33286.88
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) M0905 Methyl Dichlorophosphite [Phosphitylating Agent] 10G ₹7500 2022-05-26 Buy
Sigma-Aldrich(India) 235229 Methyl dichlorophosphite technical grade 10G ₹9937.35 2022-06-14 Buy
Sigma-Aldrich(India) 235229 Methyl dichlorophosphite technical grade 50G ₹33286.88 2022-06-14 Buy

Properties

Melting point :-91 °C (lit.)
Boiling point :93-95 °C (lit.)
Density :1.376 g/mL at 20 °C (lit.)
refractive index :n20/D 1.474(lit.)
Flash point :104 °F
storage temp. :−20°C
solubility :soluble in Chloroform, Dichloromethane, Ethyl Acetate
form :liquid
color :Colorless to Almost colorless
Water Solubility :Reacts with water. Soluble in chloroform, dichloromethane and ethyl acetate.
Sensitive :Moisture Sensitive
BRN :1697452
Stability :Flammable.
CAS DataBase Reference :3279-26-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Methyl phosphorodichloridite is a reagent for the phosphite coupling method of oligonucleotide synthesis. It is employed in the preparation of phosphonamidate- and phosphonate-linked phosphonopeptides, 2-(2-iodophenyl)ethyl methyl phosphite derivative of an alcohol, deoxyoligonucleotides on a polymer support, cis- and trans-2-oxo-2-propionyl-1,3,2-oxazaphosphorinane, phosphorodichloridothioates and oxazaphosphorinanes.

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