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URSODEOXYCHOLIC-2,2,4,4-D4 ACID

URSODEOXYCHOLIC-2,2,4,4-D4 ACID Structure
  • ₹0
  • Product name: URSODEOXYCHOLIC-2,2,4,4-D4 ACID
  • CAS: 347841-46-7
  • MF: C24H40O4
  • MW: 392.58
  • EINECS:
  • MDL Number:MFCD01317390
  • Synonyms:URSODEOXYCHOLIC-2,2,4,4-D4 ACID;Ursodeoxycholic-d4 Acid;(4R)-4-[(3R,5R,7S,8R,9S,10S,13R,14S,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;(4R)-4-[(3R,5R,7S,8R,9S,10S,13R,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;Ursodiol-d4 (Ursodeoxycholic Acid-d4);Ursodeoxycholic acid-[d4] (Solution);URSODEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 95% CHEMICAL PURITY;URSODEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly),
form :Solid
color :White to Off-White
Stability :Hygroscopic

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Ursodeoxycholic acid-d4 (UDCA-d4) is intended for use as an internal standard for the quantification of UDCA (Item No. 15121) by GC- or LC-MS. UDCA is a secondary bile acid formed via epimerization of chenodeoxycholic acid (CDCA; ). UDCA is also a metabolite of lithocholic acid (LCA; ) in human liver microsomes. It inhibits taurocholic acid uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC50 value of 3.6 μM. UDCA (50 μM) inhibits apoptosis induced by deoxycholic acid (DCA; Item Nos. 20756 | 18231) or ethanol in primary rat hepatocytes. Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.

More related product prices

64480-66-6 Ursodeoxycholic acid URSODEOXYCHOLIC ACID-24-13C URSODEOXYCHOLIC ACID ACYL-B-D-GLUCURONIDE (4R)-4-[(3S,5R,8S,9S,10S,12S,13R,14S)-1,3,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid (4R)-4-[(3S,5S,7S,8S,9S,10R,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid (3b,5b,7a,12a)-3,7,12-trihydroxy-Cholan-24-oic acid (3a,5b,6b,7a)-3,6,7-trihydroxy-Cholan-24-oic acid (3α,5β,7β)- 3,7,22-Trihydroxycholan-24-oic Acid LITHOCHOLIC ACID 3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID Deoxyursocholic acid methyl ester 4-[(5S,7S,8S,10S,13R,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid Chenodeoxycholic acid (3a,5b,6b,7b)-3,6,7-trihydroxy-Cholan-24-oic acid Methyl 3-ketoallocholate Deoxycholic acid Cholic acid 1β,3α,7β-Trihydroxy-5β-cholanic Acid (3a,5b,6a,7b)-3,6,7-trihydroxy-Cholan-24-oic acid

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Suppliers and manufacturers

CLEARSYNTH LABS LTD. Pharmaffiliates Analytics and Synthetics P. Ltd
Hangzhou MolCore BioPharmatech Co.,Ltd. ChemStrong Scientific Co.,Ltd TCI (Shanghai) Chemical Trading Co., Ltd. Manhag Testing Technology Co., Ltd HX Pharmaceutical technology co., LTD Shanghai isotope chemical co.,ltd S.Z. PhyStandard Bio-Tech. Co., Ltd. Nanjing Shizhou Biology Technology Co.,Ltd