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3-(4-FLUOROBENZOYL)PROPIONIC ACID

3-(4-FLUOROBENZOYL)PROPIONIC ACID Structure
  • ₹1612 - ₹20800
  • Product name: 3-(4-FLUOROBENZOYL)PROPIONIC ACID
  • CAS: 366-77-8
  • MF: C10H9FO3
  • MW: 196.18
  • EINECS:206-679-1
  • MDL Number:MFCD00002793
  • Synonyms:HALOPERIDOL METABOLITE III;LABOTEST-BB LT00233221;3-(4'-FLUOROBENZOYL)PROPIONIC ACID;3-(4-FLUOROBENZOYL)PROPIONIC ACID;4-(4-FLUOROPHENYL)-4-OXOBUTANOIC ACID;4-(4-FLUOROPHENYL)-4-OXOBUTYRIC ACID;AKOS BBS-00006441;4-FLUORO-R-OXO-BENZENEBUTANOIC ACID
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • ALFA India

Package

  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberF0379
  • Product description3-(4-Fluorobenzoyl)propionic Acid min. 97.0 %
  • Packaging5G
  • Price₹4600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberF0379
  • Product description3-(4-Fluorobenzoyl)propionic Acid min. 97.0 %
  • Packaging25G
  • Price₹20800
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-A13755-14
  • Product description3-(4-Fluorobenzoyl)propionic acid, 97%
  • Packaging25g
  • Price₹9060
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-A13755-06
  • Product description3-(4-Fluorobenzoyl)propionic acid, 97%
  • Packaging5g
  • Price₹1612
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) F0379 3-(4-Fluorobenzoyl)propionic Acid min. 97.0 % 5G ₹4600 2022-05-26 Buy
TCI Chemicals (India) F0379 3-(4-Fluorobenzoyl)propionic Acid min. 97.0 % 25G ₹20800 2022-05-26 Buy
ALFA India ALF-A13755-14 3-(4-Fluorobenzoyl)propionic acid, 97% 25g ₹9060 2022-05-26 Buy
ALFA India ALF-A13755-06 3-(4-Fluorobenzoyl)propionic acid, 97% 5g ₹1612 2022-05-26 Buy

Properties

Melting point :100-102 °C (lit.)
Boiling point :374.4±22.0 °C(Predicted)
Density :1.2441 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :Chloroform (Slightly), Methanol (Slightly)
form :powder to crystal
pka :4.50±0.17(Predicted)
color :White to Orange to Green
Water Solubility :Insoluble in water.
BRN :958145
CAS DataBase Reference :366-77-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

7-Fluoro-1-tetralone was prepared from 3-(4-fluorobenzoyl)-propionic acid by Wolff-Kishner reduction followed by ring closure with polyphosphoric acid and other substituted 1-tetralones where commercially available. Reduction of 3-(4-fluorobenzoyl)propionic acid with an excess of tert-butylamine borane (TBAB) in the presence of AlCl3 provided 4-(4-fluorophenyl)-1-butanol (87) in 63% yield for the synthesis of LM-1507 sodium salt. Penfluridol 1-[4,4-bis(4-fluorophenyl)butyl]-4-(4-chloro-3-trifluoromethylphenyl)- 4-hydroxypiperidine, C 28 H 27 ClF 5 NO, M r 523.99, mp 105 - 107°C, is obtained by reducing the ketone of 3-(4-fluorobenzoyl)propionic acid into a lactone.

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