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17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA

17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA Structure
  • ₹0
  • Product name: 17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA
  • CAS: 38344-08-0
  • MF: C23H32O5
  • MW: 388.5
  • EINECS:
  • MDL Number:MFCD00135254
  • Synonyms:9ALPHA,11ALPHA-15S-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;17-phenyl-18,19,20-trinorprostaglandin F2 alpha;(5Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentan-1α-yl]-5-heptenoic acid;(5Z,13E,15S)-9α,11α,15-Trihydroxy-17-phenyl-18,19,20-trinorprosta-5,13-diene-1-oic acid;(5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-17-phenyl-18,19,20-trinorprosta-5,13-diene-1-oic acid;17-Phenyl-18,19,20-trinorprostaglandin F2α;17-Phenyltrinorprostagrandin F2α;U-35687
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :82-84°C
Boiling point :597.4±50.0 °C(Predicted)
Density :1.219±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under Inert Atmosphere
solubility :Dichloromethane (Slightly), DMSO (Slightly), Methanol (Slightly)
pka :4.76±0.10(Predicted)
form :Solid
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger GHS hazard pictograms
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor. It binds to the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. At the rat recombinant FP receptor expressed in CHO cells bimatoprost inhibits PGF2α binding with a Ki of 1.1 nM. The isopropyl ester of 17-phenyl trinor PGF2α ethyl amide is slightly better than PGF2α isopropyl ester in reducing the intraocular pressure in the cat eye without any irritation.

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Suppliers and manufacturers

OPULENT PHARMA Chemicea Pharmaceuticals Pvt Ltd Varanous Labs Pvt Ltd LANSPHARMA CLEARSYNTH LABS LTD. SynZeal Research Pvt Ltd Pharmaffiliates Analytics and Synthetics P. Ltd Vasudha Pharma Chem Limited Pharma Affiliates
Shanghai Daken Advanced Materials Co.,Ltd