LAT-NET
- ₹0
- Product name: LAT-NET
- CAS: 607351-44-0
- MF: C25H39NO4
- MW: 417.58
- EINECS:
- MDL Number:MFCD03412001
- Synonyms:LATANOPROST ETHYL AMIDE;LAT-NET;N-ETHYL-9ALPHA, 11ALPHA, 15R-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR PROST 5Z-EN-1-AMIDE;13,14-Dihydro Bimatoprost;(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-N-ethylhept-5-enamide;Bimatoprost Impurity 20;5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-N-ethyl-, (5Z)-
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Properties
Boiling point :640.9±55.0 °C(Predicted)
Density :1.095±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 50 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 200 μg/ml
pka :14.84±0.70(Predicted)
Density :1.095±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 50 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 200 μg/ml
pka :14.84±0.70(Predicted)
Safety Information
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Description
Latanoprost ethyl amide (Lat-NEt) is a latanoprost analog in which the C-1 carboxyl group has been modified to an N-ethyl amide. Prostaglandin esters have been shown to have ocular hypotensive activity. Prostaglandin N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs. Although it has been claimed that prostaglandin ethyl amides are not converted to the free acids in vivo, studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 μg/g corneal tissue/hr. Lat-NEt would be expected to show the typical intraocular effects of Latanoprost free acid, but with the much slower hydrolysis pharmacokinetics of the prostaglandin N-amides.Related product price
- (-)-Corey Lactone Diol
₹17287.53 - Latanoprost
₹9700-90875.88
Suppliers and manufacturers
SynZeal Research Pvt Ltd
Hubei Aiputi Bioengineering Co., Ltd.
Shanghai Zerui Biotechnology Co., Ltd.
Nanjing Tengyi Biotechnology Co., Ltd
Shenzhen Roark Pharma-Tec Co., Ltd.
Shanghai Yifei Biotechnology Co. , Ltd.
TargetMol Chemicals Inc.
Cayman Chemical Company
Toronto Research Chemicals
Shanghai Hao Zhun Biological Technology Co., Ltd.