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ChemicalBook > Product Catalogue >Analytical Chemistry >Analysis reagents >Derivatization reagent >2-Methoxyethoxymethyl chloride

2-Methoxyethoxymethyl chloride

2-Methoxyethoxymethyl chloride Structure
  • ₹3074.3 - ₹38000
  • Product name: 2-Methoxyethoxymethyl chloride
  • CAS: 3970-21-6
  • MF: C4H9ClO2
  • MW: 124.57
  • EINECS:223-589-8
  • MDL Number:MFCD00000888
  • Synonyms:ALKOXYETHOXYMETHYLCHLORIDE;BETA-METHOXYETHOXYMETHYL CHLORIDE;ETHYLENE GLYCOL CHLOROMETHYL METHYL ETHER;1-(Chloromethoxy)-2-methoxyethane~MEM chloride;Alcoxyethoxymethylchloride;Methoxxxy ethoxy Chloromethane;2-Methoxyethoxymethyl chloride, technical grade;2-METHOXYETHOXYMETHYL CHLORIDE
6 prices
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Brand

  • ALFA India
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5g
  • 25ML
  • 25g
  • 500ML
  • ManufacturerALFA India
  • Product numberALF-L01050-06
  • Product description2-Methoxyethoxymethyl chloride, 94%
  • Packaging5g
  • Price₹3503
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-L01050-14
  • Product description2-Methoxyethoxymethyl chloride, 94%
  • Packaging25g
  • Price₹8318
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM0680
  • Product description2-Methoxyethoxymethyl Chloride min. 95.0 %
  • Packaging25ML
  • Price₹7800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM0680
  • Product description2-Methoxyethoxymethyl Chloride min. 95.0 %
  • Packaging500ML
  • Price₹38000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number357480
  • Product description2-Methoxyethoxymethyl chloride technical grade
  • Packaging5G
  • Price₹3074.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number357480
  • Product description2-Methoxyethoxymethyl chloride technical grade
  • Packaging25G
  • Price₹12946.7
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-L01050-06 2-Methoxyethoxymethyl chloride, 94% 5g ₹3503 2022-05-26 Buy
ALFA India ALF-L01050-14 2-Methoxyethoxymethyl chloride, 94% 25g ₹8318 2022-05-26 Buy
TCI Chemicals (India) M0680 2-Methoxyethoxymethyl Chloride min. 95.0 % 25ML ₹7800 2022-05-26 Buy
TCI Chemicals (India) M0680 2-Methoxyethoxymethyl Chloride min. 95.0 % 500ML ₹38000 2022-05-26 Buy
Sigma-Aldrich(India) 357480 2-Methoxyethoxymethyl chloride technical grade 5G ₹3074.3 2022-06-14 Buy
Sigma-Aldrich(India) 357480 2-Methoxyethoxymethyl chloride technical grade 25G ₹12946.7 2022-06-14 Buy

Properties

Melting point :200-202 °C
Boiling point :50-52 °C/13 mmHg (lit.)
Density :1.091 g/mL at 25 °C (lit.)
refractive index :n20/D 1.427(lit.)
Flash point :>230 °F
storage temp. :2-8°C
solubility :Chloroform, Methanol
form :Liquid
Specific Gravity :1.091
color :Clear colorless to yellow
Water Solubility :It hydrolyzes with water.
Sensitive :Moisture Sensitive
BRN :1900576
Exposure limits :ACGIH: TWA 0.001 ppm
InChIKey :BIAAQBNMRITRDV-UHFFFAOYSA-N
CAS DataBase Reference :3970-21-6(CAS DataBase Reference)
NIST Chemistry Reference :«BETA»-methoxyethoxymethyl chloride(3970-21-6)
EPA Substance Registry System :Ethane, 1-(chloromethoxy)-2-methoxy- (3970-21-6)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger GHS hazard pictograms P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

2-Methoxyethoxymethyl chloride, is used as selectively cleaved under aprotic conditions in the presence of a wide range of OH-protected reagents. It is used as an OH-protecting reagent. An examples of the target molecule MEM Chloride is the side chain of roxithromycin. It is also used in the protection of the OH groups in serine and threonine during peptide synthesis. Some of the other applications include have the ability to coordinate to metals, which is thought to accelerate the cleavage by Lewis acids. The chelating ability of the MEM ether also makes it useful as a stereodirecting group in organometallic reactions, first noted in the stereo controlled addition of ?-methoxyvinyllithium to a carbonyl in the synthesis of taxusin.

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