2-Methoxyethoxymethyl chloride
- CAS No.
- 3970-21-6
- Chemical Name:
- 2-Methoxyethoxymethyl chloride
- Synonyms
- MEM CHLORIDE;1-CHLOROMETHOXY-2-METHOXYETHANE;MEM Chlordie;MEM chloride,94%;2-Methoxyethoxymethy;2-MethoxyethoxymethyL;1-Chloro-2,5-dioxahexane;Roxithromycin side chain;Roxithromycin Impurity 15;METHOXYETHOXYCHLOROMETHANE
- CBNumber:
- CB6332734
- Molecular Formula:
- C4H9ClO2
- Molecular Weight:
- 124.57
- MOL File:
- 3970-21-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/3/28 17:11:29
Melting point | 200-202 °C |
---|---|
Boiling point | 50-52 °C/13 mmHg (lit.) |
Density | 1.091 g/mL at 25 °C (lit.) |
refractive index |
n |
Flash point | >230 °F |
storage temp. | 2-8°C |
solubility | Chloroform, Methanol |
form | Liquid |
Specific Gravity | 1.091 |
color | Clear colorless to yellow |
Water Solubility | It hydrolyzes with water. |
Sensitive | Moisture Sensitive |
BRN | 1900576 |
Exposure limits | ACGIH: TWA 0.001 ppm |
InChIKey | BIAAQBNMRITRDV-UHFFFAOYSA-N |
CAS DataBase Reference | 3970-21-6(CAS DataBase Reference) |
NIST Chemistry Reference | «BETA»-methoxyethoxymethyl chloride(3970-21-6) |
EPA Substance Registry System | Ethane, 1-(chloromethoxy)-2-methoxy- (3970-21-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS02,GHS06,GHS08 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H226-H302-H315-H319-H331-H335-H350 | |||||||||
Precautionary statements | P210-P301+P312-P303+P361+P353-P304+P340+P311-P305+P351+P338-P308+P313 | |||||||||
Hazard Codes | T | |||||||||
Risk Statements | 45-10-36/37/38-20/21/22-46-40-23/24/25-20/22 | |||||||||
Safety Statements | 53-26-36/37/39-45-16-23 | |||||||||
RIDADR | UN 2810 6.1/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
F | 10-21 | |||||||||
Hazard Note | Toxic | |||||||||
TSCA | Yes | |||||||||
HazardClass | 3 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29091990 | |||||||||
NFPA 704 |
|
2-Methoxyethoxymethyl chloride price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 357480 | 2-Methoxyethoxymethyl chloride technical grade | 3970-21-6 | 5G | ₹3074.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 357480 | 2-Methoxyethoxymethyl chloride technical grade | 3970-21-6 | 25G | ₹12946.7 | 2022-06-14 | Buy |
ALFA India | ALF-L01050-14 | 2-Methoxyethoxymethyl chloride, 94% | 3970-21-6 | 25g | ₹8318 | 2022-05-26 | Buy |
ALFA India | ALF-L01050-06 | 2-Methoxyethoxymethyl chloride, 94% | 3970-21-6 | 5g | ₹3503 | 2022-05-26 | Buy |
TCI Chemicals (India) | M0680 | 2-Methoxyethoxymethyl Chloride min. 95.0 % | 3970-21-6 | 25ML | ₹7800 | 2022-05-26 | Buy |
2-Methoxyethoxymethyl chloride Chemical Properties,Uses,Production
Chemical Properties
CLEAR COLOURLESS LIQUID
Uses
2-Methoxyethoxymethyl Chloride is an OH-protecting reagent. 2-Methoxyethoxymethyl Chloride is used in the modification of antibiotics.
Purification Methods
Possible impurities are methoxyethanol (b 124o/atm), HCHO and HCl which can be removed below the boiling point of MEMCl. Purify MEMCl by fractional distillation in a vacuum. If too impure, prepare it from methoxyethanol (152g) and s-trioxane (66g) by bubbling a stream of dry HCl (with stirring) until a clear mixture is obtained. Dilute with pentane (900mL), dry (3hours over 100g MgSO4, at 5o), evaporate and the residue is distilled in a vacuum. It is MOISTURE SENSITIVE and TOXIC. The MEM.NEt3+Cl-salt, prepared by reaction with 1.3 equivalents of Et3N (16hours/25o) and dried in a vacuum, has m 58-61o, and is moisture sensitive. [Corey et al. Tetrahedron Lett 809 1976, Yoshimatsu et al. J Org Chem 59 1011 1994, Greene & Wuts Protective Groups in Organic Synthesis edn, J Wiley & Sons NY 1991.] Carcinogen.
2-Methoxyethoxymethyl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
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Sris Synthesis Pvt Ltd., | +91-9989522441 +91-9989522441 | Hyderabad, India | 282 | 58 | Inquiry |
AMINO ORGANICS | +919866989891 | Hyderabad, India | 275 | 58 | Inquiry |
JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
anjali labs | +91-9763681015 +91-9860682220 | Maharashtra, India | 19 | 58 | Inquiry |
OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
S. R. Chemical Specialities | 08048965126 | Hyderabad, India | 90 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Sris Synthesis Pvt Ltd., | 58 |
AMINO ORGANICS | 58 |
JSK Chemicals | 58 |
anjali labs | 58 |
OCEAN TRADING CORPORATION | 58 |
A.J Chemicals | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Alfa Aesar | 58 |
CLEARSYNTH LABS LTD. | 58 |
S. R. Chemical Specialities | 58 |