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4-HYDROXYPHENYLRETINAMIDE

4-HYDROXYPHENYLRETINAMIDE Structure
  • ₹9200 - ₹47796.6
  • Product name: 4-HYDROXYPHENYLRETINAMIDE
  • CAS: 65646-68-6
  • MF: C26H33NO2
  • MW: 391.55
  • EINECS:200-256-5
  • MDL Number:MFCD00792674
  • Synonyms:4-HYDROXYPHENYLRETINAMIDE;4HPR;FENRETINIDE;p-Hydroxyphenylretinamide;4-HPR, Fenretinide, N-(4-Hydroxyphenyl)retinamide;(2E,4E,6E,8E)-N-(4-Hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenamide;Fenretinimide;Fenretinide(4-HPR)
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 400μL
  • 5MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberH1464
  • Product descriptionall-trans-N-(4-Hydroxyphenyl)retinamide
  • Packaging10MG
  • Price₹9200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberH1464
  • Product descriptionall-trans-N-(4-Hydroxyphenyl)retinamide
  • Packaging100MG
  • Price₹14500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number390900
  • Product description4-Hydroxyphenylretinamide - CAS 65646-68-6 - Calbiochem A synthetic amide of all-trans retinoic acid (RA) that displays reduced toxicity relative to RA while maintaining significant biological activity.
  • Packaging5MG
  • Price₹19050
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberH7779
  • Product descriptionRetinoic acid p-hydroxyanilide ≥95%
  • Packaging5MG
  • Price₹21487.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSAB1301585
  • Product descriptionANTI-HPR (CENTER) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution
  • Packaging400μL
  • Price₹47796.6
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) H1464 all-trans-N-(4-Hydroxyphenyl)retinamide 10MG ₹9200 2022-05-26 Buy
TCI Chemicals (India) H1464 all-trans-N-(4-Hydroxyphenyl)retinamide 100MG ₹14500 2022-05-26 Buy
Sigma-Aldrich(India) 390900 4-Hydroxyphenylretinamide - CAS 65646-68-6 - Calbiochem A synthetic amide of all-trans retinoic acid (RA) that displays reduced toxicity relative to RA while maintaining significant biological activity. 5MG ₹19050 2022-06-14 Buy
Sigma-Aldrich(India) H7779 Retinoic acid p-hydroxyanilide ≥95% 5MG ₹21487.63 2022-06-14 Buy
Sigma-Aldrich(India) SAB1301585 ANTI-HPR (CENTER) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution 400μL ₹47796.6 2022-06-14 Buy

Properties

Melting point :162-163°C
Boiling point :597.6±42.0 °C(Predicted)
Density :1.081±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Orange solid
pka :9.98±0.26(Predicted)
color :Yellow
λmax :362nm(MeOH)(lit.)
Merck :14,3998
Stability :Light Sensitive - Protect from Light Exposure
InChIKey :AKJHMTWEGVYYSE-FXILSDISSA-N
CAS DataBase Reference :65646-68-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Fenretinide is a synthetic retinoic acid that induces ceramide in tumor cell lines, leading to caspase-dependent apoptosis (IC50 = 2.4 μM). It promotes the generation of reactive oxygen species, the degradation of anti-apoptotic MCL-1, and the cleavage of pro-apoptotic PKCδ. At 5-20 μM, fenretinide selectively activates retinoic acid receptor γ and is reported to inhibit the growth of Caov-3, OVCAR-3, and SK-OV-3 ovarian cancer cells with IC50 values of 3.7, 6.9, and 8.2 μM, respectively.

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Suppliers and manufacturers

career henan chemical co
4-HYDROXYPHENYLRETINAMIDE
₹5.00 /5KG
4-HYDROXYPHENYLRETINAMIDE CAS:65646-68-6
TCI Chemicals (India) Pvt. Ltd. Pharmaffiliates Analytics and Synthetics P. Ltd A.J Chemicals CLEARSYNTH LABS LTD.
ATK CHEMICAL COMPANY LIMITED
Shenzhen Nexconn Pharmatechs Ltd
BOC Sciences
SIMAGCHEM CORP
TargetMol Chemicals Inc.