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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Urine (urea) pyrimidine >4-THIOURACIL

4-THIOURACIL

4-THIOURACIL Structure
  • ₹2244 - ₹11000
  • Product name: 4-THIOURACIL
  • CAS: 591-28-6
  • MF: C4H4N2OS
  • MW: 128.15
  • EINECS:
  • MDL Number:MFCD00090842
  • Synonyms:4-Thiouracil97%;4-Thiouracil 97%;2(1H)-Pyrimidinone, 3,4-dihydro-4-thioxo- (9CI);4-Thiouracil ,98%;4-Thioxo-1H-pyrimidin-2-one;2-HYDROXY-4-MERCAPTOPYRIMIDINE / 4-THIOURACIL;4-thiouracyl;4-sulfanylidene-1,2,3,4-tetrahydropyriMidin-2-one
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ALFA India

Package

  • 250mg
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberT2757
  • Product description4-Thiouracil
  • Packaging1G
  • Price₹11000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number440736
  • Product description4-Thiouracil 97%
  • Packaging1G
  • Price₹7858.95
  • Updated2022-06-14
  • Buy
  • ManufacturerALFA India
  • Product numberALF-H61919-03
  • Product description4-Thiouracil, 97%
  • Packaging1g
  • Price₹5390
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-H61919-MD
  • Product description4-Thiouracil, 97%
  • Packaging250mg
  • Price₹2244
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) T2757 4-Thiouracil 1G ₹11000 2022-05-26 Buy
Sigma-Aldrich(India) 440736 4-Thiouracil 97% 1G ₹7858.95 2022-06-14 Buy
ALFA India ALF-H61919-03 4-Thiouracil, 97% 1g ₹5390 2022-05-26 Buy
ALFA India ALF-H61919-MD 4-Thiouracil, 97% 250mg ₹2244 2022-05-26 Buy

Properties

Melting point :295 °C (dec.) (lit.)
Density :1.368 (estimate)
refractive index :1.7000 (estimate)
storage temp. :Store at -20°C
solubility :1 M NaOH: soluble50mg/mL
form :Powder
pka :5.38±0.20(Predicted)
color :Yellow
CAS DataBase Reference :591-28-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Description

4-Thiouracil is a site-specific, photoactivatable probe used to detect RNA structures and nucleic acid-nucleic acid contacts. It absorbs ultraviolet light >300 nm and, in the presence of oxygen, acts as an energy donor to produce singlet oxygen by triplet-triplet energy transfer. The highly reactive oxygen species then reacts readily with 4-thiouracil, leading to the production of uracil and uracil-6-sulfonate, which is fluorescent at a wavelength of ~390 nm. 4-Thiouracil is used as a T. gondii uracil phosphoribosyltransferase substrate to produce 4-thiouridine monophosphate, which can ultimately be incorporated into RNA.

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