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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >Pyridine compound >Aminopyridine >4-Aminopyridine

4-Aminopyridine

4-Aminopyridine Structure
  • ₹470 - ₹73252
  • Product name: 4-Aminopyridine
  • CAS: 504-24-5
  • MF: C5H6N2
  • MW: 94.11
  • EINECS:207-987-9
  • MDL Number:MFCD00006439
  • Synonyms:4-AMINOPYRIDINE,REAGENT;AMINOPYRIDINE, 4-(P);PARA-AMINOPYRIDINE;4-AMINO PYRIDINE PYRIDIN-4-YLAMINE;Phillips 1861;phillips1861 ;Pimadin (free base);Prc 1237
Price21 Properties Safety Information Description
21 prices
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Brand

  • Sigma-Aldrich
  • ALFA India
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • SRL
  • ottokemi

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  • ManufacturerSigma-Aldrich
  • Product number36687
  • Product description4-Aminopyridine PESTANAL?, analytical standard
  • Packaging1G
  • Price₹2955.23
  • Updated2022-06-14
  • Buy
  • ManufacturerALFA India
  • Product numberALF-A12405-18
  • Product description4-Aminopyridine, 98%
  • Packaging50g
  • Price₹4931
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-A12405-30
  • Product description4-Aminopyridine, 98%
  • Packaging250g
  • Price₹6828
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-A12405-0B
  • Product description4-Aminopyridine, 98%
  • Packaging1000g
  • Price₹73252
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA0414
  • Product description4-Aminopyridine min. 99.0 %
  • Packaging25G
  • Price₹2300
  • Updated2022-05-26
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  • ManufacturerTCI Chemicals (India)
  • Product numberA0414
  • Product description4-Aminopyridine min. 99.0 %
  • Packaging100G
  • Price₹5300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA0414
  • Product description4-Aminopyridine min. 99.0 %
  • Packaging500G
  • Price₹17500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number36687
  • Product description4-Aminopyridine PESTANAL?, analytical standard
  • Packaging1G
  • Price₹2955.23
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA78403
  • Product description4-Aminopyridine 98%
  • Packaging25G
  • Price₹3204.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number275875
  • Product description4-Aminopyridine ≥99%
  • Packaging1G
  • Price₹3377.4
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number8.01111
  • Product description4-Aminopyridine for synthesis
  • Packaging10G
  • Price₹4150
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number8.01111
  • Product description4-Aminopyridine for synthesis
  • Packaging25G
  • Price₹5000
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA78403
  • Product description4-Aminopyridine 98%
  • Packaging100G
  • Price₹7057.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number275875
  • Product description4-Aminopyridine ≥99%
  • Packaging5G
  • Price₹8584.23
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number16104
  • Product description4-Aminopyridine pure, 98%
  • Packaging100Gms
  • Price₹3390
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number16104
  • Product description4-Aminopyridine pure, 98%
  • Packaging25Gms
  • Price₹1000
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 36687 4-Aminopyridine PESTANAL?, analytical standard 1G ₹2955.23 2022-06-14 Buy
ALFA India ALF-A12405-18 4-Aminopyridine, 98% 50g ₹4931 2022-05-26 Buy
ALFA India ALF-A12405-30 4-Aminopyridine, 98% 250g ₹6828 2022-05-26 Buy
ALFA India ALF-A12405-0B 4-Aminopyridine, 98% 1000g ₹73252 2022-05-26 Buy
TCI Chemicals (India) A0414 4-Aminopyridine min. 99.0 % 25G ₹2300 2022-05-26 Buy
TCI Chemicals (India) A0414 4-Aminopyridine min. 99.0 % 100G ₹5300 2022-05-26 Buy
TCI Chemicals (India) A0414 4-Aminopyridine min. 99.0 % 500G ₹17500 2022-05-26 Buy
Sigma-Aldrich(India) 36687 4-Aminopyridine PESTANAL?, analytical standard 1G ₹2955.23 2022-06-14 Buy
Sigma-Aldrich(India) A78403 4-Aminopyridine 98% 25G ₹3204.2 2022-06-14 Buy
Sigma-Aldrich(India) 275875 4-Aminopyridine ≥99% 1G ₹3377.4 2022-06-14 Buy
Sigma-Aldrich(India) 8.01111 4-Aminopyridine for synthesis 10G ₹4150 2022-06-14 Buy
Sigma-Aldrich(India) 8.01111 4-Aminopyridine for synthesis 25G ₹5000 2022-06-14 Buy
Sigma-Aldrich(India) A78403 4-Aminopyridine 98% 100G ₹7057.9 2022-06-14 Buy
Sigma-Aldrich(India) 275875 4-Aminopyridine ≥99% 5G ₹8584.23 2022-06-14 Buy
SRL 16104 4-Aminopyridine pure, 98% 100Gms ₹3390 2022-05-26 Buy
SRL 16104 4-Aminopyridine pure, 98% 25Gms ₹1000 2022-05-26 Buy
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Properties

Melting point :155-158 °C (lit.)
Boiling point :273 °C (lit.)
Density :1.26
vapor pressure :0.046Pa at 25℃
refractive index :1.5560 (estimate)
Flash point :156°C
storage temp. :2-8°C
solubility :H2O: soluble50mg/mL, clear, colorless
form :Crystalline Powder, Solid or Crystals
pka :9.114(at 25℃)
color :White to faint grey to light yellow
Water Solubility :Soluble in water(112 g/L at 20 deg C). Soluble in ethyl ether, benzene. Slightly soluble in ligroin. Very soluble in ethanol. Soluble in methanol, acetone, tetrahydrofuran, isopropanol, acetonitrile, N,N-dimethylformamide, dimethylsulfoxide, and ethanol.
Merck :14,3933
BRN :105782
Stability :Hygroscopic
InChIKey :NUKYPUAOHBNCPY-UHFFFAOYSA-N
LogP :-0.76 at pH7.4
CAS DataBase Reference :504-24-5(CAS DataBase Reference)
NIST Chemistry Reference :4-Pyridinamine(504-24-5)
EPA Substance Registry System :4-Aminopyridine (504-24-5)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

4-Aminopyridine (4-AP) is a non-selective blocker of voltage-dependent K+-channels (Kv proteins in the KCN gene family). It has greatest potency at Kv1 (KCNA) and Kv3 (KCNC) family members (IC50s = 290, 590, 195, 13, 29, and 100 μM for subunits 1.1, 1.2, 1.3, 1.4, 3.1, and 3.2, respectively). 4-AP also blocks Kv2 and Kv4 subunits at millimolar concentrations. When administered orally, 4-AP has benefits against multiple sclerosis, while injection into the brain produces epileptiform activity and can be used to study seizures.

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