4-HYDROXYISOLEUCINE
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- ₹36729.23 - ₹38079
- Product name: 4-HYDROXYISOLEUCINE
- CAS: 55399-93-4
- MF: C6H13NO3
- MW: 147.17
- EINECS:2017-001-1
- MDL Number:MFCD07357252
- Synonyms:4-HYDROXYISOLEUCINE; 4-HYDROXY-L-ISOLEUCINE;HIL;HYDROXYISOLEUCINE, 4-;2-AMINO-2,3,5-TRIDEOXY-3-METHYL-D-XYLONIC ACID;(2S,3R,4S)-4-HYDROXYISOLEUCINE MAJOR ISOMER AND (2R,3R,4S)-4-HYDROXYISOLEUCINE MINOR ISOMER;[DISCONTINUED] Replaced by KIT-00008502-0HK;HYDROXYISOLEUCINE, 4-(FG);(2S,3R,4S)-2-Amino-4-hydroxy-3-methylpentanoic acid
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
- ottokemi
Package
- 50MG
- ManufacturerSigma-Aldrich(India)
- Product number50118
- Product description(4S)-4-Hydroxy-L-isoleucine from fenugreek seeds, ≥98.0% (TLC)
- Packaging50MG
- Price₹36729.23
- Updated2022-06-14
- Buy
- Manufacturerottokemi
- Product number H 1633
- Product description(4S)-4-Hydroxy-L-isoleucine 98%
- Packaging50mg
- Price₹38079
- Updated2022-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 50118 | (4S)-4-Hydroxy-L-isoleucine from fenugreek seeds, ≥98.0% (TLC) | 50MG | ₹36729.23 | 2022-06-14 | Buy |
| ottokemi | H 1633 | (4S)-4-Hydroxy-L-isoleucine 98% | 50mg | ₹38079 | 2022-05-26 | Buy |
Properties
Melting point :223-224℃
Boiling point :331.6±32.0 °C(Predicted)
Density :1.181±0.06 g/cm3 (20 ºC 760 Torr)
Flash point :147℃
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Methanol (Slightly), Water (Slightly)
pka :2.41±0.25(Predicted)
form :Solid
color :White to Off-White
optical activity :[α]/D +32.5±2.0°, c = 1 in H2O
BRN :4128096
InChI :InChI=1S/C6H13NO3/c1-3(4(2)8)5(7)6(9)10/h3-5,8H,7H2,1-2H3,(H,9,10)/t3-,4-,5-/m0/s1
InChIKey :OSCCDBFHNMXNME-YUPRTTJUSA-N
SMILES :C(O)(=O)[C@@H](N)[C@@H](C)[C@H](C)O
Boiling point :331.6±32.0 °C(Predicted)
Density :1.181±0.06 g/cm3 (20 ºC 760 Torr)
Flash point :147℃
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Methanol (Slightly), Water (Slightly)
pka :2.41±0.25(Predicted)
form :Solid
color :White to Off-White
optical activity :[α]/D +32.5±2.0°, c = 1 in H2O
BRN :4128096
InChI :InChI=1S/C6H13NO3/c1-3(4(2)8)5(7)6(9)10/h3-5,8H,7H2,1-2H3,(H,9,10)/t3-,4-,5-/m0/s1
InChIKey :OSCCDBFHNMXNME-YUPRTTJUSA-N
SMILES :C(O)(=O)[C@@H](N)[C@@H](C)[C@H](C)O
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
4-Hydroxyisoleucine is an amino acid that has been found in fenugreek (T. foenum graecum) seeds and has antidiabetic activity. It increases glucose-stimulated insulin release from isolated rat islets and isolated perfused rat pancreas when used at a concentration of 200 μM. In vivo, 4-hydroxyisoleucine increases PI3K activity in muscle and liver in rats when administered at a dose of 18 mg/kg and in muscle in a rat model of type 2 diabetes induced by nicotinamide and streptozotocin (STZ; ) when administered at 25 mg/kg. 4-Hydroxyisoleucine (50 mg/kg per day for four weeks) decreases plasma glucose, triglyceride, LDL, HDL, and cholesterol levels in an STZ-induced rat model of type 1 diabetes.Related product price
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