4-HYDROXYPHENYLRETINAMIDE
- ₹9200 - ₹47796.6
- Product name: 4-HYDROXYPHENYLRETINAMIDE
- CAS: 65646-68-6
- MF: C26H33NO2
- MW: 391.55
- EINECS:200-256-5
- MDL Number:MFCD00792674
- Synonyms:4-HYDROXYPHENYLRETINAMIDE;4HPR;FENRETINIDE;p-Hydroxyphenylretinamide;4-HPR, Fenretinide, N-(4-Hydroxyphenyl)retinamide;(2E,4E,6E,8E)-N-(4-Hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenamide;Fenretinimide;Fenretinide(4-HPR)
5 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 10MG
- 400μL
- 5MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberH1464
- Product descriptionall-trans-N-(4-Hydroxyphenyl)retinamide
- Packaging10MG
- Price₹9200
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberH1464
- Product descriptionall-trans-N-(4-Hydroxyphenyl)retinamide
- Packaging100MG
- Price₹14500
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number390900
- Product description4-Hydroxyphenylretinamide - CAS 65646-68-6 - Calbiochem A synthetic amide of all-trans retinoic acid (RA) that displays reduced toxicity relative to RA while maintaining significant biological activity.
- Packaging5MG
- Price₹19050
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberH7779
- Product descriptionRetinoic acid p-hydroxyanilide ≥95%
- Packaging5MG
- Price₹21487.63
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSAB1301585
- Product descriptionANTI-HPR (CENTER) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution
- Packaging400μL
- Price₹47796.6
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | H1464 | all-trans-N-(4-Hydroxyphenyl)retinamide | 10MG | ₹9200 | 2022-05-26 | Buy |
TCI Chemicals (India) | H1464 | all-trans-N-(4-Hydroxyphenyl)retinamide | 100MG | ₹14500 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | 390900 | 4-Hydroxyphenylretinamide - CAS 65646-68-6 - Calbiochem A synthetic amide of all-trans retinoic acid (RA) that displays reduced toxicity relative to RA while maintaining significant biological activity. | 5MG | ₹19050 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | H7779 | Retinoic acid p-hydroxyanilide ≥95% | 5MG | ₹21487.63 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SAB1301585 | ANTI-HPR (CENTER) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 400μL | ₹47796.6 | 2022-06-14 | Buy |
Properties
Melting point :162-163°C
Boiling point :597.6±42.0 °C(Predicted)
Density :1.081±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Orange solid
pka :9.98±0.26(Predicted)
color :Yellow
λmax :362nm(MeOH)(lit.)
Merck :14,3998
Stability :Light Sensitive - Protect from Light Exposure
InChIKey :AKJHMTWEGVYYSE-FXILSDISSA-N
CAS DataBase Reference :65646-68-6(CAS DataBase Reference)
Boiling point :597.6±42.0 °C(Predicted)
Density :1.081±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Orange solid
pka :9.98±0.26(Predicted)
color :Yellow
λmax :362nm(MeOH)(lit.)
Merck :14,3998
Stability :Light Sensitive - Protect from Light Exposure
InChIKey :AKJHMTWEGVYYSE-FXILSDISSA-N
CAS DataBase Reference :65646-68-6(CAS DataBase Reference)
Safety Information
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Description
Fenretinide is a synthetic retinoic acid that induces ceramide in tumor cell lines, leading to caspase-dependent apoptosis (IC50 = 2.4 μM). It promotes the generation of reactive oxygen species, the degradation of anti-apoptotic MCL-1, and the cleavage of pro-apoptotic PKCδ. At 5-20 μM, fenretinide selectively activates retinoic acid receptor γ and is reported to inhibit the growth of Caov-3, OVCAR-3, and SK-OV-3 ovarian cancer cells with IC50 values of 3.7, 6.9, and 8.2 μM, respectively.Related product price
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