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2-Bromo-4'-Benzyloxy-3'-nitroacetophenone

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone Structure
  • ₹0
  • Product name: 2-Bromo-4'-Benzyloxy-3'-nitroacetophenone
  • CAS: 43229-01-2
  • MF: C15H12BrNO4
  • MW: 350.16
  • EINECS:610-115-3
  • MDL Number:MFCD06797599
  • Synonyms:2-BROMO-4'-BENZYLOXY-3'-NITROACETOPHENONE;ALPHA-BROMO 4-BENZYLOXY-3-NITRO ACETOPHENONE;1-(4-(benzyloxy)-3-nitrophenyl)-2-bromoethan-1-one;Formoterol Bromide;2-Bromo-1-[3-Nitro-4-(Phenylmethoxy)Phenyl]Ethanone;2-Bromo-1-[3-nitro-4-(phenylmethoxy)phenyl]-ethanone;3-BroMo-1-[3-Nitro-4-(PhenylMethoxy)phenyl]Ethanone;Formoterol Intermediate
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :135-137 °C(Solv: ethanol (64-17-5))
Boiling point :465.2±35.0 °C(Predicted)
Density :1.517±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :Soluble in Methylene chloride, sparingly soluble in ethyl acetate, insoluble in water
form :Solid
color :Pale yellow to cream coloured crystalline powder
CAS DataBase Reference :43229-01-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

1-(4-(Benzyloxy)-3-nitrophenyl)-2-bromoethanone, can be used as an intermediate in the synthesis of Arformoterol Tartrate (A767505), which is a derivative of Arformoterol, a long acting beta-adrenoceptor agonist drug indicated for the treatment of chronic obstructive pulmonary disease (COPD).

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