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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >Atorvastatin Related Compound A

Atorvastatin Related Compound A

Atorvastatin Related Compound A Structure
  • ₹60598.35
  • Product name: Atorvastatin Related Compound A
  • CAS: 433289-83-9
  • MF: C33H35CaN2O5+
  • MW: 579.7194
  • EINECS:
  • MDL Number:MFCD11977955
  • Synonyms:Atorvastatin EP IMpurity A;Desfluoro Atorvastatin Calcium Salt;(betaR,deltaR)-beta,delta-Dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid calcium salt (2:1);Atorvastatin Impurity A;(βR,δR)-β,δ-Dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemicalcium salt;Calcium (3R,5R)-3,5-dihydroxy-7-(2-isopropyl-4,5-diphenyl-3-(phenylcarbamoyl)-1H-pyrrol-1-yl)h;ATORVASTATIN DESFLUORO IMPURITY;Atorvastatin Related Compound A (20 mg) (Desfluoro impurity, or (3R,5R)-7-[3-(phenylcarbamoyl)-2-isopropyl-4,5- diphenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium salt)
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 30MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1868
  • Product descriptionAtorvastatin Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging30MG
  • Price₹60598.35
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) PHR1868 Atorvastatin Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material 30MG ₹60598.35 2022-06-14 Buy

Properties

Melting point :150℃ (decomposition)
solubility :DMSO (Slightly), Methanol (Slightly)
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Desfluoro Atorvastatin is an impurity in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.

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