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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >RofluMilast related substance

RofluMilast related substance

RofluMilast related substance Structure
  • ₹0
  • Product name: RofluMilast related substance
  • CAS: 475271-62-6
  • MF: C16H14Cl2N2O3
  • MW: 353.2
  • EINECS:
  • MDL Number:MFCD23703091
  • Synonyms:RofluMilast related substance B;Roflumilast Impurity B;RofluMilast IMpurity 5;RofluMilast IMp.B;4-O-Des(difluoroMethyl) RofluMilast;3-(CyclopropylMethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-hydroxybenzaMide;3-(cyclopropylMethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzaMide;Benzamide, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-hydroxy-
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :179-182°C
Boiling point :448.6±45.0 °C(Predicted)
Density :1.489±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,Room Temperature
solubility :Acetone, Methanol
pka :7.40±0.45(Predicted)
form :Solid
color :White to Pale Yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

4-O-Des(difluoromethyl) Roflumilast is an impurity in the preparation of Roflumilast (R639700).

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