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ChemicalBook > Product Catalogue >Biochemical Engineering >Nucleoside drugs >Deoxynucleotides and their analogs >5-CHLORO-2'-DEOXYURIDINE

5-CHLORO-2'-DEOXYURIDINE

5-CHLORO-2'-DEOXYURIDINE Structure
  • ₹8919.8
  • Product name: 5-CHLORO-2'-DEOXYURIDINE
  • CAS: 50-90-8
  • MF: C9H11ClN2O5
  • MW: 262.65
  • EINECS:
  • MDL Number:MFCD00006531
  • Synonyms:2'-DEOXY-5-CHLOROURIDINE;5-CHLORODESOXYURIDINE;5-CHLORO-2'-DEOXYURIDINE;5-chloro-2’-deoxy-uridin ;5-Chlorodeoxyuridin;5-Chloro-2'-deoxy-D-uridine;5-CHLORODEOXYURIDINE;Chlorodeoxyuridine
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 100MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberC6891
  • Product description5-Chloro-2′-deoxyuridine thymidine analog
  • Packaging100MG
  • Price₹8919.8
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) C6891 5-Chloro-2′-deoxyuridine thymidine analog 100MG ₹8919.8 2022-06-14 Buy

Properties

Melting point :176-179°C
Density :1.5507 (rough estimate)
refractive index :1.6500 (estimate)
storage temp. :-20°C
solubility :DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form :Solid
pka :7.73±0.10(Predicted)
color :White to Off-White
CAS DataBase Reference :50-90-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

5-Chloro-2'-deoxyuridine (CldU) is a thymidine analog that is readily incorporated, following phosphorylation, into newly synthesized DNA in place of thymidine. Like 5-bromo-2’-deoxyuridine and 5-iodo-2’-deoxyuridine, CldU can be detected immunologically in cells and tissues. CldU can also be added to cells or tissues sequentially with another thymidine analog to label temporally distinct populations. The insertion of thymidine analogs, including CldU, can significantly alter DNA processing and replication, so these analogs have also been used as mutagens, clastogens, and antiviral compounds.

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