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ChemicalBook > Product Catalogue >Organic Chemistry >Amides >Amino compound >5-Dehydro Tolvaptan

5-Dehydro Tolvaptan

5-Dehydro Tolvaptan Structure
  • ₹0
  • Product name: 5-Dehydro Tolvaptan
  • CAS: 137973-76-3
  • MF: C26H23ClN2O3
  • MW: 446.93
  • EINECS:1312995-182-4
  • MDL Number:MFCD19440797
  • Synonyms:N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methylbenzamide;7-chloro-1-[2-methyl-4-[(2-methylbenzoyl)amino]benzoyl]-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine;N-(4-(7-Chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbe;5-Dehydro Tolvaptan ;N-(4-(7-Chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-Methylphenyl)-2-MethylbenzaMide;Dehydrotolvaptan;N-[4-[7-Chloro-2,3,4,5-Tetrahydro-5-oxo-1H-1-Benzazepine-1-yl)carbonyl]-3-MethylPhenyl]-2-MethylBenzamide;N-[4-(7-chloro-5-oxo-3,4-dihydro-2H-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-methylbenzamide
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :>118°C (dec.)
Boiling point :593.2±50.0 °C(Predicted)
Density :1.307
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :12.97±0.70(Predicted)
color :White to Off-White
InChIKey :VENGMROMZOKURN-UHFFFAOYSA-N
SMILES :C(NC1=CC=C(C(N2C3=CC=C(Cl)C=C3C(=O)CCC2)=O)C(C)=C1)(=O)C1=CC=CC=C1C

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P501 Dispose of contents/container to..…

Description

5-Dehydro Tolvaptan is an impurity of Tolvaptan (T536650), a selective, competitive arginine vasopressin V2 receptor antagonist ngestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).

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