5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazolehydrobromide
![5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazolehydrobromide Structure](/CAS/GIF/511296-88-1.gif)
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- ₹8500 - ₹30000
- Product name: 5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazolehydrobromide
- CAS: 511296-88-1
- MF: C16H16N2S.HBr
- MW: 349
- EINECS:
- MDL Number:MFCD02683960
- Synonyms:5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazolehydrobromide;Cyclic Pifithrin-α hydrobromide;Pifithrin-beta;Cyclic Pifithrin-alpha HydrobroMide;5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazolehydrobromide Pifithrin-β;2-(4-Methylphenyl)imidazo[2,1-b]-5,6,7,8-tetrahydrobenzothiazole hydrobromide;Cyclic PFT-α hydrobromide;Pifithrin-α, cyclic
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 10MG
- 20MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberC2826
- Product descriptionCyclic Pifithrin-α Hydrobromide
- Packaging20MG
- Price₹8500
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberC2826
- Product descriptionCyclic Pifithrin-α Hydrobromide
- Packaging100MG
- Price₹30000
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP4236
- Product descriptionCyclic Pifithrin-α hydrobromide ≥98% (HPLC)
- Packaging5MG
- Price₹17038.55
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP4236
- Product descriptionCyclic Pifithrin-α hydrobromide ≥98% (HPLC)
- Packaging10MG
- Price₹28415.63
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | C2826 | Cyclic Pifithrin-α Hydrobromide | 20MG | ₹8500 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C2826 | Cyclic Pifithrin-α Hydrobromide | 100MG | ₹30000 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | P4236 | Cyclic Pifithrin-α hydrobromide ≥98% (HPLC) | 5MG | ₹17038.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P4236 | Cyclic Pifithrin-α hydrobromide ≥98% (HPLC) | 10MG | ₹28415.63 | 2022-06-14 | Buy |
Properties
storage temp. :-20°C
solubility :DMSO: soluble20mg/mL
form :powder to crystal
color :White to Almost white
Merck :14,7421
solubility :DMSO: soluble20mg/mL
form :powder to crystal
color :White to Almost white
Merck :14,7421
Safety Information
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Description
Pifithrin-α (PFT-α; ) is a reversible inhibitor of p53-dependent transcription and apoptosis. Cyclic PFT-α, also known as PFT-β, is a stable analog of PFT-α, formed by the condensation of pifithrin-α in solution. It inhibits the growth of the cancer cell lines IGROV-1, A2780, and HCT116 (IC50 = 23, 77, and 103 μM, respectively). At doses lower than those that inhibit growth, cyclic PFT-α induces autophagy in HCT116 cells and sensitizes IGROV-1 and H460 cells to anti-microtubule agents. In addition, 10 μM cyclic PFT-α blocks p53-dependent protection from DNA damage, induced by hydrogen peroxide or ultraviolet radiation, in melanocytes.Related product price
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Suppliers and manufacturers
career henan chemical co
![5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazolehydrobromide](https://img.chemicalbook.com/ProductImageEN/2019-12/small/1113a923-acfb-4d03-ac9d-6927d4fc7f9a.jpg)
A.J Chemicals
CLEARSYNTH LABS LTD.
TCI Chemicals (India) Pvt. Ltd.
ATK CHEMICAL COMPANY LIMITED
Shaanxi Dideu Medichem Co. Ltd
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Dayang Chem (Hangzhou) Co.,Ltd.
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
₹1.00 /1g
5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazolehydrobromide CAS:511296-88-1
5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazolehydrobromide CAS:511296-88-1