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3-Amino-1H-pyrazole-4-carboxamide

3-Amino-1H-pyrazole-4-carboxamide Structure
  • ₹0
  • Product name: 3-Amino-1H-pyrazole-4-carboxamide
  • CAS: 5334-31-6
  • MF: C4H6N4O
  • MW: 126.12
  • EINECS:226-252-3
  • MDL Number:MFCD00082808
  • Synonyms:5-Amino-1H-pyrazole-4-carboxylic amide;3-Amino-1H-pyrazole-4-carboxamide;5-azanyl-1H-pyrazole-4-carboxamide;3-AMINO-PYRAZOLE-4-CARBOXYLIC ACID AMIDE;5-Amino-1H-pyrazole-4-car...;3-AMino-1H-pyrazole-4-car...;3-AMino-1H-pyrazole-4-carboxylic aMide;Allopurinol EP IMpurity A
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :187-189 °C(Solv: water (7732-18-5))
Boiling point :454.3±25.0 °C(Predicted)
Density :1.538±0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :DMSO (Slightly), Methanol (Very Slightly)
form :Solid
pka :13.26±0.50(Predicted)
color :Off-White to Pale Beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

5-Amino-4-pyrazolecarboxamide is used in the synthesis of 4H-3,1-Benzothiazinone analogs as antiproliferative agents against human cancer cell lines. Also, it is an intermediate used in the synthesis of 3-(4H-1,2,4-Triazol-4-yl)-1H-pyrazole-4-carboxamide (T767570), which is an impurity of Allopurinol (A547300), which is a xanthine oxidase inhibitor; decreases uric acid production. Used in treatment of hyperuricemia and chronic gout. Antiurolithic.

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Suppliers and manufacturers

GSV speciality chemicals ALS INDIA LIFE SCIENCES SRC Laboratories Pvt Ltd CLEARSYNTH LABS LTD. A.J Chemicals Pharmaffiliates Analytics and Synthetics P. Ltd SynZeal Research Pvt Ltd Pharma Affiliates VASIN BIO LIFE SCIENCES PVT LTD
ATK CHEMICAL COMPANY LIMITED