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AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT

AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Structure
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  • Product name: AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT
  • CAS: 54472-66-1
  • MF: C78H108N18O21S2
  • MW: 1697.95
  • EINECS:
  • MDL Number:MFCD08459563
  • Synonyms:H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH (DISULFIDE BRIDGE: 3-14), ACETATE SALT;AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT;SOMATOSTATIN 14, ACETATE;Somatostatin monoacetate;GHIH;Somatostatin (sheep), monoacetate (salt);Somatostatin-14 (human, mouse, rat, porcine, bovine, ovine) (acetate);Cyclic somatostatin Acetate
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Properties

storage temp. :Store at -20°C
solubility :Water: 0.3 mg/ml
form :A powder

Safety Information

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Description

Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin. It is a somatostatin (SST) receptor agonist that binds to SST1, SST2, SST3, SST4, and SST5 (IC50s = 0.22, 0.10, 0.28, 1.23, and 0.30 nM, respectively, in CCL39 cells expressing human recombinant receptors). It inhibits cAMP accumulation induced by forskolin in CCL39 cells expressing human recombinant SST1, SST2, SST3, SST4, and SST5 (EC50s = 6.16, 4.37, 17.38, 2.95, and 4.67 nM, respectively). Somatostatin-14 inhibits the release of growth hormone, prolactin, thyrotropin, glucagon, and insulin, as well as other signaling molecules.

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