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ChemicalBook > Product Catalogue >Chemical Reagents >Organic reagents >Hydroxylamine >BENZENESULFOHYDROXAMIC ACID

BENZENESULFOHYDROXAMIC ACID

BENZENESULFOHYDROXAMIC ACID Structure
  • ₹5500 - ₹14000
  • Product name: BENZENESULFOHYDROXAMIC ACID
  • CAS: 599-71-3
  • MF: C6H7NO3S
  • MW: 173.19
  • EINECS:209-973-8
  • MDL Number:MFCD00025013
  • Synonyms:benzsulfo-hydroxamicaci ;benzsulfohydroxamicacid ;Hydroxamic acid, benzsulfo-;Hydroxylamine, N-(phenylsulfonyl)-;N-(Phenylsulfonyl)hydroxylamine;n-hydroxy-benzenesulfonamid ;N-Hydroxybenzenesulfonimidic acid;BENZENESULFOHYDROXAMIC ACID
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberH0203
  • Product descriptionBenzenesulfohydroxamic Acid
  • Packaging5G
  • Price₹5500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberH0203
  • Product descriptionBenzenesulfohydroxamic Acid
  • Packaging25G
  • Price₹14000
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) H0203 Benzenesulfohydroxamic Acid 5G ₹5500 2022-05-26 Buy
TCI Chemicals (India) H0203 Benzenesulfohydroxamic Acid 25G ₹14000 2022-05-26 Buy

Properties

Melting point :122-125 °C
Boiling point :351.5±25.0 °C(Predicted)
Density :1.342 (estimate)
refractive index :1.5500 (estimate)
storage temp. :2-8°C
solubility :DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; PBS (pH7.2): 2 mg/ml
pka :9.29(at 25℃)
form :solid
Merck :14,7426
CAS DataBase Reference :599-71-3(CAS DataBase Reference)
EPA Substance Registry System :Benzenesulfonamide, N-hydroxy- (599-71-3)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Piloty’s Acid is one of the most commonly used nitroxyl (HNO) donors, decomposing to form HNO and benzenesulfinate anion under basic conditions. HNO is the one electron reduced form of nitric oxide (NO), which has been indicated in a variety of processes in the body, including regulation of vascular tone and neuronal signaling. The rate of HNO release by Piloty’s acid at pH 7.0 is very slow (t = 5500 minutes), making its use most effective above pH 8.0. As pH increases, the half-life of Piloty’s acid decreases to 561, 90, and 33 minutes at pH 8.0, 9.0, and 10.0, respectively. Piloty’s acid also inhibits yeast aldehyde dehydrogenase (ALDH) with an IC50 of 48 μM.

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