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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Urine (urea) pyrimidine >6-Chlorouracil

6-Chlorouracil

6-Chlorouracil Structure
  • ₹4269 - ₹54666.25
  • Product name: 6-Chlorouracil
  • CAS: 4270-27-3
  • MF: C4H3ClN2O2
  • MW: 146.53
  • EINECS:224-258-0
  • MDL Number:MFCD00014595
  • Synonyms:6-chloro-1H-pyrimidine-2,4-dione;Chlorouracil;6-Chlorouracil ,99%;2,4(1H,3H)-Pyrimidinedione, 6-chloro- (9CI);6-Chlorouracil,98+%;4-Chloro-2,6-dihydroxypyrimidine, 6-Chloro-2,4-dihydroxypyrimidine, 6-Chlorouracil;AURORA KA-4918;6 - chlorine uracil
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Brand

  • ALFA India
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1g
  • 5g
  • 10G
  • 25G
  • ManufacturerALFA India
  • Product numberALF-L01875-03
  • Product description6-Chlorouracil, 98+%
  • Packaging1g
  • Price₹4269
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-L01875-06
  • Product description6-Chlorouracil, 98+%
  • Packaging5g
  • Price₹14740
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC2093
  • Product description6-Chlorouracil
  • Packaging5G
  • Price₹5500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC2093
  • Product description6-Chlorouracil
  • Packaging25G
  • Price₹11800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC9525
  • Product description4-Chlorouracil ≥99%
  • Packaging10G
  • Price₹54666.25
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-L01875-03 6-Chlorouracil, 98+% 1g ₹4269 2022-05-26 Buy
ALFA India ALF-L01875-06 6-Chlorouracil, 98+% 5g ₹14740 2022-05-26 Buy
TCI Chemicals (India) C2093 6-Chlorouracil 5G ₹5500 2022-05-26 Buy
TCI Chemicals (India) C2093 6-Chlorouracil 25G ₹11800 2022-05-26 Buy
Sigma-Aldrich(India) C9525 4-Chlorouracil ≥99% 10G ₹54666.25 2022-06-14 Buy

Properties

Melting point :290-295°C
Boiling point :300°C
Density :1.61±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Soluble in Ammonium Hydroxide
pka :6.24±0.10(Predicted)
form :Solid
color :White
Water Solubility :4.885g/L(25 ºC)
BRN :120492
InChI :InChI=1S/C4H3ClN2O2/c5-2-1-3(8)7-4(9)6-2/h1H,(H2,6,7,8,9)
InChIKey :PKUFNWPSFCOSLU-UHFFFAOYSA-N
SMILES :C1(=O)NC(Cl)=CC(=O)N1
CAS DataBase Reference :4270-27-3(CAS DataBase Reference)
NIST Chemistry Reference :6-Chlorouracil(4270-27-3)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Chlorouracil (4-Chlorouracil; 6-Chlorouracil) is a halogenated uracil that is useful in studies of the effects of halogenation on nucleic acid base-pair stability and alkali metal ion affinity. Reaction of 6-chlorouracil with 4-(dimethylamino)pyridine, 4-methylpyridine, and pyridin-4-yl-morpholine yielded pyridinium-substituted uracils as chlorides which were converted into pyridinium uracilates by deprotonation. These heterocyclic mesomeric betaines are cross-conjugated and thus possess separate cationic (pyridinium) and anionic (uracilate) moieties. Calculations and X-ray single crystal analyses may be used to characterize these systems and to compare the salts with the betaines.

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