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ChemicalBook > Product Catalogue >Biochemical Engineering >Chinese Herbs >6-Shogaol

6-Shogaol

6-Shogaol Structure
  • ₹55055.95 - ₹86470.1
  • Product name: 6-Shogaol
  • CAS: 555-66-8
  • MF: C17H24O3
  • MW: 276.37
  • EINECS:
  • MDL Number:MFCD01736094
  • Synonyms:(E)-1-(4-Hydroxy-3-methoxy-phenyl)dec-4-en-3-one;6-SHOGAOL;SHOGAOL;SHOGAOL, 6-;4-Decen-3-one, 1-(4-hydroxy-3-methoxyphenyl);6-Shagaol;1-(3-Methoxy-4-hydroxyphenyl)-4-decene-3-one;1-(4-Hydroxy-3-methoxyphenyl)-4-decen-3-one
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product number39303
  • Product description[6]-Shogaol analytical standard
  • Packaging10MG
  • Price₹55055.95
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSMB00311
  • Product descriptionShogaol ≥90% (HPLC)
  • Packaging50MG
  • Price₹86470.1
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 39303 [6]-Shogaol analytical standard 10MG ₹55055.95 2022-06-14 Buy
Sigma-Aldrich(India) SMB00311 Shogaol ≥90% (HPLC) 50MG ₹86470.1 2022-06-14 Buy

Properties

Boiling point :427.5±35.0 °C(Predicted)
Density :1.0448 g/cm3(Temp: 25 °C)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka :10.01±0.20(Predicted)
form :Liquid
color :Colourless to Light Yellow
Odor :Mild, warm-herbaceous, sweet odor
BRN :2056098
InChI :InChI=1S/C17H24O3/c1-3-4-5-6-7-8-15(18)11-9-14-10-12-16(19)17(13-14)20-2/h7-8,10,12-13,19H,3-6,9,11H2,1-2H3
InChIKey :OQWKEEOHDMUXEO-BQYQJAHWSA-N
SMILES :C(C1=CC=C(O)C(OC)=C1)CC(=O)C=CCCCCC
LogP :3.789 (est)
CAS DataBase Reference :555-66-8(CAS DataBase Reference)
NIST Chemistry Reference :6-shogaol(555-66-8)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

6-Shogaol is a minor, bioactive component of ginger (Zingiber officinale Roscoe) with anti-inflammatory and anticancer properties. It is present in fresh ginger at low levels, but quantities of 6-shogaol are significantly increased in dried ginger. 6-Shogaol induces apoptosis in cancer cells through the production of reactive oxygen species and the activation of caspase, impairs tubulin polymerization, downregulates NF-κB signaling, inhibits the expression of inflammatory mediators, and suppresses Toll-like receptor signaling. 6-Shogaol-rich extracts have been shown to enhance antioxidant defense mechanisms by inducing Nrf2/ARE-mediated gene expression in cell and animal models. It can also activate both TRPV1 and TRPA1 channels (EC50s = 0.32 and 16 μM, respectively).

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