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Isoquinoline, 1,7-dichloro-4-Methoxy-

Isoquinoline, 1,7-dichloro-4-Methoxy- Structure
  • ₹7800
  • Product name: Isoquinoline, 1,7-dichloro-4-Methoxy-
  • CAS: 630423-36-8
  • MF: C10H7Cl2NO
  • MW: 228.07
  • EINECS:
  • MDL Number:MFCD17012717
  • Synonyms:1,7-dichloro-4-Methoxyisoquinoline;Isoquinoline, 1,7-dichloro-4-Methoxy-;Asunaprevir Intermediate 2;Asunaprevir N-1
1 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberD5182
  • Product description1,7-Dichloro-4-methoxyisoquinoline min. 98.0 %
  • Packaging1G
  • Price₹7800
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D5182 1,7-Dichloro-4-methoxyisoquinoline min. 98.0 % 1G ₹7800 2022-05-26 Buy

Properties

Melting point :137.0 to 142.0 °C
Boiling point :355.7±37.0 °C(Predicted)
Density :1.384±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
form :powder to crystal
pka :0.98±0.34(Predicted)
color :White to Yellow to Orange

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

1,7-Dichloro-4-methoxyisoquinoline acts as a reagent in the synthesis and biological evaluations of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease. Preparation, SAR of methoxyisoquinoline derivatives and discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection.

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