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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antiviral drugs >Asunaprevir

Asunaprevir

Asunaprevir Structure
  • ₹0
  • Product name: Asunaprevir
  • CAS: 630420-16-5
  • MF: C35H46ClN5O9S
  • MW: 748.29
  • EINECS:681-328-7
  • MDL Number:MFCD27987900
  • Synonyms:(1R,2S)-N-[(1,1-Dimethylethoxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[(7-chloro-4-methoxy-1-isoquinolinyl)oxy]-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenylcyclopropanecarboxamide;Asunaprevir;BMS 650032;Asunaprevir (BMS-650032);BMS 650032/Asunaprevir;Asunaprevir API;tert-butyl N-[(2S)-1-[(2S,4R)-4-(7-chloro-4-methoxyisoquinolin-1-yl)oxy-2-[[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]carbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate;BMS-650032; BMS 650032; BMS650032
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :149-150oC
Density :1.37
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
form :Solid
pka :4.49±0.40(Predicted)
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Sold under the trade name Sunvepra®, asunaprevir received approval in Japan as part of a combination treatment for the hepatitis C virus (HCV). Working in concert with daclatasvir (IX) (vide infra), asunaprevir is a unique treatment for HCV, as it is free from both interferon and ribavirin and is administered orally. This direct-acting anti-viral, which was developed by Bristol–Myers Squibb (BMS), works as an NS3/4A protease inhibitor, representing a valuable treatment option for patient populations who are unable to receive, or do not respond to, the standard course of treatment—peginterferon/ribavirin.

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630423-36-8

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Suppliers and manufacturers

career henan chemical co
Asunaprevir
₹2.00 /1kg
Asunaprevir CAS:630420-16-5
Dideu Industries Group Limited
Asunaprevir USP/EP/BP
₹1.10 /1g
Asunaprevir USP/EP/BP CAS:630420-16-5
Wuhan Fortuna Chemical Co., Ltd
Asunaprevir
₹0.00 /1g/Bag
Asunaprevir CAS:630420-16-5
A.J Chemicals CLEARSYNTH LABS LTD.
Shanghai Daken Advanced Materials Co.,Ltd
BOC Sciences
Chongqing Chemdad Co., Ltd
AFINE CHEMICALS LIMITED
Baoji Guokang Bio-Technology Co., Ltd.