2,3,4,5-TETRA-(4-PYRIDYL) THIOPHENE
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- ₹12427.1 - ₹49849.13
- Product name: 2,3,4,5-TETRA-(4-PYRIDYL) THIOPHENE
- CAS: 64048-12-0
- MF: C24H16N4S
- MW: 392.48
- EINECS:200-258-5
- MDL Number:MFCD01103196
- Synonyms:¥-(2,3,4,5-Thiophentetrayl)tetrakis-pyridine;,4¥4,4¥Nsc75503;Pyridine, 4,4',4'',4'''-(2,3,4,5-thiophenetetrayl)tetrakis-;GANT58;1,2,3,4-Tetrakis(4-pyridyl)thiophene
3 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberG8923
- Product descriptionGANT58 ≥98% (HPLC)
- Packaging5MG
- Price₹12427.1
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number373400
- Product descriptionHh/Gli Antagonist, GANT58 - CAS 64048-12-0 - Calbiochem The Hh/Gli Antagonist, GANT58, also referenced under CAS 64048-12-0, controls the biological activity of Hh/Gli. This small molecule/inhibitor is prim
- Packaging5MG
- Price₹17860
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberG8923
- Product descriptionGANT58 ≥98% (HPLC)
- Packaging25MG
- Price₹49849.13
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | G8923 | GANT58 ≥98% (HPLC) | 5MG | ₹12427.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 373400 | Hh/Gli Antagonist, GANT58 - CAS 64048-12-0 - Calbiochem The Hh/Gli Antagonist, GANT58, also referenced under CAS 64048-12-0, controls the biological activity of Hh/Gli. This small molecule/inhibitor is prim | 5MG | ₹17860 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G8923 | GANT58 ≥98% (HPLC) | 25MG | ₹49849.13 | 2022-06-14 | Buy |
Properties
Melting point :252-253℃
Boiling point :414.1±40.0 °C(Predicted)
Density :1.254
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: >10mg/mL
form :Yellow solid
pka :4.50±0.10(Predicted)
color :white to pale yellow
Boiling point :414.1±40.0 °C(Predicted)
Density :1.254
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: >10mg/mL
form :Yellow solid
pka :4.50±0.10(Predicted)
color :white to pale yellow
Safety Information
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Description
Hedgehog (hh) proteins, important regulators of development, bind the cell-surface protein Patched, allowing activation of Smoothened (Smo). In vertebrates, this ultimately leads to the activation of the zinc-finger transcription factors of the GLI family. Overactivation of this pathway contributes to certain cancers, including glioblastoma, for which the GLI proteins are named. GANT 58 is a GLI antagonist that inhibits GLI1-mediated transcription (EC50 = 5 μM) in a variety of cell types. It inhibits the hh signaling pathway downstream of Smo and the endogenous downstream inhibitor Sufu thereby affecting GLI1 nuclear accumulation. GANT 58 displays antiproliferative and antitumor activity against Ewing sarcoma family of tumor cells.More related product prices
ThiopheneRelated product price
- 64048-12-0
₹12427.1-49849.13 - Thiophene
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