Welcome to chemicalbook!
China english Japan Germany India
400-158-6606
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structured search
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
head sculpture My chemicalbook

Welcome back!

RFQ
skype
MY Account
Top

L-TRANS-PYRROLIDINE-2,4-DICARBOXYLIC ACID

L-TRANS-PYRROLIDINE-2,4-DICARBOXYLIC ACID Structure
  • ₹6895.53 - ₹22407.75
  • Product name: L-TRANS-PYRROLIDINE-2,4-DICARBOXYLIC ACID
  • CAS: 64769-66-0
  • MF: C6H9NO4
  • MW: 159.14
  • EINECS:
  • MDL Number:MFCD00153866
  • Synonyms:L-TRANS-4-CARBOXY-L-PROLINE;L-TRANS-PYRROLIDINE-2,4-DICARBOXYLIC ACID;L-TRANS-2,4-PDC;TRANS-4-CARBOXY-L-PROLINE;2,4-Pyrrolidinedicarboxylicacid,(2S,4R)-(9CI);Zinc03796127;(2S,4R)-pyrrolidine-2,4-dicarboxylic acid;(2S,4R)-2,4-Pyrrolidinedicarboxylic acid
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 2MG
  • 10MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberP7575
  • Product descriptionL-trans-Pyrrolidine-2,4-dicarboxylic acid ≥98%
  • Packaging2MG
  • Price₹6895.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP7575
  • Product descriptionL-trans-Pyrrolidine-2,4-dicarboxylic acid ≥98%
  • Packaging10MG
  • Price₹22407.75
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) P7575 L-trans-Pyrrolidine-2,4-dicarboxylic acid ≥98% 2MG ₹6895.53 2022-06-14 Buy
Sigma-Aldrich(India) P7575 L-trans-Pyrrolidine-2,4-dicarboxylic acid ≥98% 10MG ₹22407.75 2022-06-14 Buy

Properties

Melting point :214-217oC
storage temp. :Store at RT
solubility :Water (Slightly)
form :White solid.
color :White
Water Solubility :Soluble to 100 mM in water

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

L-trans-Pyrrolidine-2,4-dicarboxylic acid (L-trans-PDC) is a glutamate uptake blocker, serving as a "conformer mimic" of the glutamate molecule as recognized by EAAT (excitatory amino acid transporter) proteins. L-trans-PDC is demonstrated to increase extracellular glutamate concentration without affecting extracellular GABA levels. Blockade of glutamate uptake by L-trans-PDC has a correlated effect of inducing neuronal Ca2+ influx and massive NMDA receptor-mediated neuronal death. Specificity of L-trans-PDC for the EAAT protein over other glutamate-recognizing loci indicates a particular structural requirement for the EAAT binding site, satisfied by this structurally rigid pyrrolidine "conformer mimic" of glutamate. L-trans-Pyrrolidine-2,4-dicarboxylic acid is an inhibitor of EAAT1, EAAT2, EAAT3, EAAT4 and EAAT5.

More related product prices

(2S,4R)-4-METHYLGLUTAMIC ACID

Related product price

Suppliers and manufacturers

TargetMol Chemicals Inc.
L-trans-2,4-PDC
₹78.00 /1mg
L-trans-2,4-PDC CAS:64769-66-0
Capot Chemical Co.,Ltd.
Nextpeptide Inc
Aladdin Scientific
DAYANG CHEM (HANGZHOU) CO.,LTD Shanghai EFE Biological Technology Co., Ltd. TargetMol Chemicals Inc. Neobioscience Co., Ltd. R&D Systems, Inc Cayman Chemical Company