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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >Piperazine compounds >1-(4-Bromophenyl)piperazine

1-(4-Bromophenyl)piperazine

1-(4-Bromophenyl)piperazine Structure
  • ₹3528.95
  • Product name: 1-(4-Bromophenyl)piperazine
  • CAS: 66698-28-0
  • MF: C10H13BrN2
  • MW: 241.13
  • EINECS:
  • MDL Number:MFCD00130198
  • Synonyms:1-(4-BROMOPHENYL)PIPERAZINE;1-(4-BROMO-PHENYL)-PIPERAZINE DIHYDROCHLORIDE;CML-027;Piperazine, 1-(4-bromophenyl)-;KML-30;1-(4-Bromophenyl)
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product number724580
  • Product description1-(4-bromophenyl)piperazine 95%
  • Packaging1G
  • Price₹3528.95
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 724580 1-(4-bromophenyl)piperazine 95% 1G ₹3528.95 2022-06-14 Buy

Properties

Melting point :91-95 °C
Boiling point :353.3±27.0 °C(Predicted)
Density :1.386±0.06 g/cm3(Predicted)
storage temp. :2-8°C
pka :8.88±0.10(Predicted)
InChI :InChI=1S/C10H13BrN2/c11-9-1-3-10(4-2-9)13-7-5-12-6-8-13/h1-4,12H,5-8H2
InChIKey :PJHPFAFEJNBIDC-UHFFFAOYSA-N
SMILES :N1(C2=CC=C(Br)C=C2)CCNCC1
CAS DataBase Reference :66698-28-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Description

1-(4-Bromophenyl)piperazine (street names: 4-bromo-piperein, 4-BP, brein) is structurally related to 1-(4-fluorophenyl)piperazine and to 1-(4-chlorophenyl)piperazine. The only difference is the halogen substituent type attached to the phenyl ring's para-position. In the case of NPSs from the methcathinone group, which are also neurotransmitter releasers, structure–activity studies demonstrated that the replacement of a fluorine or chlorine atom with a bromine atom resulted in a compound with more potency for the release of both dopamine and serotonin. The lowest dopamine selectivity, an additional consequence of these halogen replacements, results in lower abuse potential in favor of empathogenic properties[1].