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ChemicalBook > Product Catalogue >API >Antibiotics >Other antibiotic Drugs >5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine

5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine

5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine Structure
  • ₹0
  • Product name: 5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine
  • CAS: 6981-18-6
  • MF: C14H18N4O2
  • MW: 274.32
  • EINECS:230-246-6
  • MDL Number:MFCD00057747
  • Synonyms:ORMETHOPRIM;ORMETOPRIM;ORMETOPRIN;OMP ;5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine;L-Ascorbic Phosphate Magnesium;2,4-DiaMino-5-92-Methyl-4,5- diMethoxybenzyl)pyriMidine;DiaMino-5-(6-Methylveratryl)pyriMidine
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :231.0 to 235.0 °C
Boiling point :521.5±60.0 °C(Predicted)
Density :1.223±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Room temperature
solubility :Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated)
form :Solid
pka :7.11±0.10(Predicted)
color :Off-White
Water Solubility :Water: Insoluble
λmax :287nm(CHCl3)(lit.)
Stability :Hygroscopic
CAS DataBase Reference :6981-18-6(CAS DataBase Reference)
EPA Substance Registry System :Ormetoprim (6981-18-6)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

It is a potent and selective inhibitor of bacterial dihydrofolate reductase, the enzyme responsible for the NADPH-dependent reduction of 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate. Antibacterial.This compound is a contaminant of emerging concern (CECs).

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