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ChemicalBook > Product Catalogue >Chemical Reagents >Organic reagents >Tricyclic compound >6(5H)-Phenanthridone

6(5H)-Phenanthridone

6(5H)-Phenanthridone Structure
  • ₹2200 - ₹7100
  • Product name: 6(5H)-Phenanthridone
  • CAS: 1015-89-0
  • MF: C13H9NO
  • MW: 195.22
  • EINECS:213-804-3
  • MDL Number:MFCD00004988
  • Synonyms:PHENANTHRIDINONE;PHENANTHRIDONE;6(5H)-Phenantridinone;6-Phenanthridinol;6-Phenanthridone;Phenantridone;2H-BENZ[C]ISOQUINOLIN-1-ONE;phenanthridin-6(5H)-one
3 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberP1998
  • Product description6(5H)-Phenanthridinone
  • Packaging1G
  • Price₹2200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP1998
  • Product description6(5H)-Phenanthridinone
  • Packaging5G
  • Price₹7100
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number299634
  • Product description6-(5H)-Phenanthridinone technical grade
  • Packaging1G
  • Price₹2727.9
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) P1998 6(5H)-Phenanthridinone 1G ₹2200 2022-05-26 Buy
TCI Chemicals (India) P1998 6(5H)-Phenanthridinone 5G ₹7100 2022-05-26 Buy
Sigma-Aldrich(India) 299634 6-(5H)-Phenanthridinone technical grade 1G ₹2727.9 2022-06-14 Buy

Properties

Melting point :290-292 °C(lit.)
Boiling point :435 °C
Density :1.230±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMF: 1mg/mL; DMF:PBS (pH 7.2) (1:5): 0.16mg/mL
form :powder to crystal
pka :13.27±0.20(Predicted)
color :White to Light yellow to Light orange
Water Solubility :Soluble in DMSO (5 mg/ml). Insoluble in water.
λmax :338nm(EtOH)(lit.)
BRN :140641
CAS DataBase Reference :1015-89-0(CAS DataBase Reference)
NIST Chemistry Reference :6(5H)-phenanthridinone(1015-89-0)
EPA Substance Registry System :6-Phenanthridinone (1015-89-0)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

6(5H)-Phenanthridinone is used as a probe into the role of PARP in cellular response to irradiation. Treatment of cells with 6(5H)-Phenanthridinone and various DNA-damaging agents showed a resistance to apoptosis. It acts as a reactant in the synthesis of 5,6-dihydrophenanthridine sulfonamides, oxidative coupling with diphenylacetylene, direct copper acetate-catalyzed N-cyclopropylation of cyclic amides. It is used as HIV-1 integrase inhibitor.

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