ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Tricyclic compound >6(5H)-Phenanthridone
6(5H)-Phenanthridone
![6(5H)-Phenanthridone Structure](CAS/GIF/1015-89-0.gif)
- CAS No.
- 1015-89-0
- Chemical Name:
- 6(5H)-Phenanthridone
- Synonyms
- PJ 97A;NSC 11021;NSC 40943;NSC 61083;WD 99-004344;Phenantridone;PHENANTHRIDONE;PHENANTHRIDINONE;6-Phenanthridone;6-Phenanthridinol
- CBNumber:
- CB3386736
- Molecular Formula:
- C13H9NO
- Molecular Weight:
- 195.22
- MOL File:
- 1015-89-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/12/11 17:28:48
Melting point | 290-292 °C(lit.) |
---|---|
Boiling point | 435 °C |
Density | 1.230±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
solubility | DMF: 1mg/mL; DMF:PBS (pH 7.2) (1:5): 0.16mg/mL |
form | powder to crystal |
pka | 13.27±0.20(Predicted) |
color | White to Light yellow to Light orange |
Water Solubility | Soluble in DMSO (5 mg/ml). Insoluble in water. |
λmax | 338nm(EtOH)(lit.) |
BRN | 140641 |
CAS DataBase Reference | 1015-89-0(CAS DataBase Reference) |
NIST Chemistry Reference | 6(5H)-phenanthridinone(1015-89-0) |
EPA Substance Registry System | 6-Phenanthridinone (1015-89-0) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H332-H335 | |||||||||
Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
Safety Statements | 22-24/25 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | SG0370000 | |||||||||
HS Code | 29337900 | |||||||||
NFPA 704 |
|
6(5H)-Phenanthridone price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 299634 | 6-(5H)-Phenanthridinone technical grade | 1015-89-0 | 1G | ₹2727.9 | 2022-06-14 | Buy |
TCI Chemicals (India) | P1998 | 6(5H)-Phenanthridinone | 1015-89-0 | 1G | ₹2200 | 2022-05-26 | Buy |
TCI Chemicals (India) | P1998 | 6(5H)-Phenanthridinone | 1015-89-0 | 5G | ₹7100 | 2022-05-26 | Buy |
6(5H)-Phenanthridone Chemical Properties,Uses,Production
Uses
6-Phenanthridone is a poly(ADP-ribose) polymerase (PARP) inhibitor with immunosuppressive effects. 6-Phenanthridone has been shown to inhibit concanavalin A-induced lymphocyte proliferation.
Definition
ChEBI: A member of the class of phenanthridines that is phenanthridine with an oxo substituent at position 6. A poly(ADP-ribose) polymerase (PARP) inhibitor, it has been shown to exhibit immunosuppressive activity.
General Description
6-(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose)polymerase (PARP)-1 activity. The ability of 6-(5H)-phenanthridinone to potentiate the effect of ionizing radiation on tumour cells was evaluated. Action of 6-(5H)-phenanthridinone, one of the most potent PARP inhibitor, on RDM4 murine lymphoma cells in culture was evaluated.
6(5H)-Phenanthridone Preparation Products And Raw materials
Raw materials
1,3-bis(2-phenylphenyl)urea
2-Aminobiphenyl
N-(2-Biphenylyl)-p-toluenesulfonamide
2-Iodobiphenyl-2'-amine
N-methoxy-[1,1'-biphenyl]-2-carboxamide
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Global( 194)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12459 | 58 | Inquiry |
Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | China | 6938 | 58 | Inquiry |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20361 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29901 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
SIMAGCHEM CORP | +86-13806087780 | China | 17367 | 58 | Inquiry |
Supplier | Advantage |
---|---|
CHEMSWORTH | 30 |
A.J Chemicals | 58 |
CLEARSYNTH LABS LTD. | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Hebei Mojin Biotechnology Co., Ltd | 58 |
Shanghai UCHEM Inc. | 58 |
Henan Fengda Chemical Co., Ltd | 58 |
career henan chemical co | 58 |
Chongqing Chemdad Co., Ltd | 58 |
SIMAGCHEM CORP | 58 |
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PHENANTHRIDINONE
PHENANTHRIDONE
6(5H)-Phenantridinone
6-Phenanthridinol
6-Phenanthridone
Phenantridone
2H-BENZ[C]ISOQUINOLIN-1-ONE
phenanthridin-6(5H)-one
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5,6-Dihydrophenanthridine-6-one
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5H-phenanthridin-6-one
NSC 11021
NSC 40943
NSC 61083
PJ 97A
WD 99-004344
phenantridine-6(5H)-one
Phenanthridone (misnomer)
6(5H)-PHENANTHRIDINONE
6(5H)-PHENANTHRIDONE
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