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N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE

N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE Structure
  • ₹7913.08 - ₹242328.45
  • Product name: N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE
  • CAS: 70967-90-7
  • MF: C27H38N6O9
  • MW: 590.63
  • EINECS:232-670-7
  • MDL Number:MFCD00077137
  • Synonyms:N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE;N-(METHOXYSUCCINYL)-L-ALANYL-L-ALANYL-L-PROLYL-L-VALINE 4-NITROANILIDE;ELASTASE SUBSTRATE I, COLORIMETRIC;MEO-SUC-ALA-ALA-PRO-VAL-PARANITROANILIDE;MEOSUC-ALA-ALA-PRO-VAL-PNA;METHOXYSUCCINYL-ALA-ALA-PRO-VAL-P-NITROANILIDE;METHOXYSUCCINYL-ALA-ALA-PRO-VAL-P-NITROANILIDE, METHANOL ADDUCT;L-Valinamide, N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-
5 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 250MG
  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product numberM4765
  • Product descriptionN-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide elastase substrate
  • Packaging10MG
  • Price₹7913.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number454454
  • Product descriptionMethoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide - CAS 70967-90-7 - Calbiochem Soluble, specific substrate for human leukocyte elastase.
  • Packaging50MG
  • Price₹14700.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM4765
  • Product descriptionN-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide elastase substrate
  • Packaging50MG
  • Price₹16540.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM4765
  • Product descriptionN-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide elastase substrate
  • Packaging250MG
  • Price₹77193.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM4765
  • Product descriptionN-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide elastase substrate
  • Packaging1G
  • Price₹242328.45
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) M4765 N-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide elastase substrate 10MG ₹7913.08 2022-06-14 Buy
Sigma-Aldrich(India) 454454 Methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide - CAS 70967-90-7 - Calbiochem Soluble, specific substrate for human leukocyte elastase. 50MG ₹14700.01 2022-06-14 Buy
Sigma-Aldrich(India) M4765 N-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide elastase substrate 50MG ₹16540.6 2022-06-14 Buy
Sigma-Aldrich(India) M4765 N-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide elastase substrate 250MG ₹77193.08 2022-06-14 Buy
Sigma-Aldrich(India) M4765 N-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide elastase substrate 1G ₹242328.45 2022-06-14 Buy

Properties

Melting point :203-205°C
Boiling point :958.4±65.0 °C(Predicted)
Density :1.297±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMF: 25 mg/mL, clear, light yellow
pka :13.29±0.20(Predicted)
form :Off-white solid
color :White to Off-White
BRN :6266359

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy pathogens. Evaluating these enzymes is helpful to understanding inflammatory autoimmune processes. MeOSuc-AAPV-pNA is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3, but not cathepsin G or chymotrypsin. Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm.

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